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BRD-A69208616-001-01-8 (CID 56846668) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Top Targets:
STKc GSK3(3)
 
 
STKc CDK5(1)
 
 
CDK5 activato..(1)
 
 
BioAssay Types:
Confirmatory(7)
 
 
BioActivity Types:
AC50(7)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 7    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID135378282]
AC50_uM 5.59e-06PathHunter bCatenin (U2-OS) Measured in Cell-Based System Using Plate Reader - 2133-06_Inhibitor_Dose_DryPowder_Activity [AID624088, Type: confirmatory]
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2
[SID135378282]
AC50_uM 0.009TCF/LEF Reporter Assay Measured in Cell-Based System Using Plate Reader - 2133-01_Inhibitor_Dose_DryPowder_Activity [AID624086, Type: confirmatory]
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3
[SID135378282]
AC50_uM 0.0357GSK3beta Measured in Biochemical System Using Plate Reader - 2046-01_Inhibitor_Dose_DryPowder_Activity [AID623998, Type: confirmatory]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
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4
[SID135378282]
AC50_uM 0.103GSK3beta Assay at Varied ATP concentrations Measured in Biochemical System Using Plate Reader - 2046-04_Inhibitor_Dose_DryPowder_Activity [AID624027, Type: confirmatory]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
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5
[SID135378282]
AC50_uM 0.51Human p-Tau and Total Tau ELISA Measured in Cell-Based System Using Plate Reader - 2133-07_Inhibitor_Dose_DryPowder_Activity [AID624057, Type: confirmatory]
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6
[SID135378282]
AC50_uM 22.16CDK5 Measured in Biochemical System Using Plate Reader - 2046-05_Inhibitor_Dose_DryPowder_Activity [AID623999, Type: confirmatory]Cyclin-dependent kinase 5, regulatory subunit 1 (p35) [Homo sapiens] [gi:20072248]
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7
[SID135378282]
AC50_uM 22.16CDK5 Measured in Biochemical System Using Plate Reader - 2046-05_Inhibitor_Dose_DryPowder_Activity [AID623999, Type: confirmatory]CDK5 [Homo sapiens] [gi:48146199]
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8
[SID135378282]
GSK3beta Surface Plasmon Resonance (SPR) Assay Measured in Biochemical System Using Microfluidics - 2133-08_Inhibitor_Dose_DryPowder_Activity [AID624108, Type: other]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
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