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AGN-PC-0BIOQ8 (CID 56840762) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(8)
 
 
Top Targets:
PTZ00371(1)
 
 
BioAssay Types:
Confirmatory(6)
 
 
BioActivity Types:
IC50(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 7    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134970503]
IC50 0.62Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (M18AAP): radiolabel-based cell-based dose response assay to identify compounds that inhibit P. falciparum growth in RBCs, Set 2. [AID743024, Type: confirmatory]
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2
[SID134970503]
Average Hum18AAP IC50 13.61Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the human M18 Aspartyl Aminopeptidase (hM18AAP) (3) [AID624174, Type: confirmatory]
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3
[SID134970503]
Average PFM18AAP IC50 14.8QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (2) [AID624177, Type: confirmatory]
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4
[SID134970503]
Avg CC50 50Vero Cytoxicity Assay: A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (3) [AID624205, Type: confirmatory]
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5
[SID134970503]
Average PFM17LAP IC50 73.37Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID624175, Type: confirmatory]
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6
[SID134970503]
Average PFM1AAP IC50 74.63Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) (3) [AID624176, Type: confirmatory]
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7
[SID134970503]
Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (M18AAP): radiolabel-based cell-based assay to identify compounds that inhibit P. falciparum growth in RBCs, Set2 [AID720736, Type: other]
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8
[SID134970503]
Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (M18AAP): radiolabel-based cell-based assay to identify compounds that inhibit P. falciparum growth in RBCs, Set2 [AID720736_1, Type: other]M18 aspartyl aminopeptidase [Plasmodium falciparum 3D7] [gi:124507185]
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