Bookmark and Share
BRD-K94990229-001-01-7 (CID 56840724) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(13)
 
 
Inactive(1)
 
 
Unspecified(1)
 
 
Top Targets:
STKc GSK3(4)
 
 
 
 
CDK5 activato..(1)
 
 
STKc CDK5(1)
 
 
BioAssay Types:
Confirmatory(7)
 
 
BioActivity Types:
AC50(7)
 
 
IC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 15   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134970447]
AC50_uM 3.27e-06PathHunter bCatenin (U2-OS) Measured in Cell-Based System Using Plate Reader - 2133-06_Inhibitor_Dose_DryPowder_Activity [AID624088, Type: confirmatory]
View
2
[SID134970447]
AC50_uM 0.005TCF/LEF Reporter Assay Measured in Cell-Based System Using Plate Reader - 2133-01_Inhibitor_Dose_DryPowder_Activity [AID624086, Type: confirmatory]
View
3
[SID134970447]
GSK3a IC50 0.0077874Dose responses of selected compounds against GSK3b Measured in Biochemical System Using Plate Reader - 2133-10_Inhibitor_Dose_DryPowder_Activity [AID624091_5, Type: other]
View
4
[SID134970447]
GSK3b IC50 0.0154766Dose responses of selected compounds against GSK3b Measured in Biochemical System Using Plate Reader - 2133-10_Inhibitor_Dose_DryPowder_Activity [AID624091_6, Type: other]
View
5
[SID134970447]
AC50_uM 0.037GSK3beta Measured in Biochemical System Using Plate Reader - 2046-01_Inhibitor_Dose_DryPowder_Activity [AID623998, Type: confirmatory]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
View
6
[SID134970447]
CDK5/p25 IC50 0.127253Dose responses of selected compounds against GSK3b Measured in Biochemical System Using Plate Reader - 2133-10_Inhibitor_Dose_DryPowder_Activity [AID624091_4, Type: other]
View
7
[SID134970447]
AC50_uM 0.231GSK3beta Assay at Varied ATP concentrations Measured in Biochemical System Using Plate Reader - 2046-04_Inhibitor_Dose_DryPowder_Activity [AID624027, Type: confirmatory]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
View
8
[SID134970447]
CDK2/CycE1 IC50 0.427327Dose responses of selected compounds against GSK3b Measured in Biochemical System Using Plate Reader - 2133-10_Inhibitor_Dose_DryPowder_Activity [AID624091_3, Type: other]
View
9
[SID134970447]
AC50_uM 0.461CDK5 Measured in Biochemical System Using Plate Reader - 2046-05_Inhibitor_Dose_DryPowder_Activity [AID623999, Type: confirmatory]Cyclin-dependent kinase 5, regulatory subunit 1 (p35) [Homo sapiens] [gi:20072248]
View
10
[SID134970447]
AC50_uM 0.461CDK5 Measured in Biochemical System Using Plate Reader - 2046-05_Inhibitor_Dose_DryPowder_Activity [AID623999, Type: confirmatory]CDK5 [Homo sapiens] [gi:48146199]
View
11
[SID134970447]
CDK2/CycA2 IC50 0.561127Dose responses of selected compounds against GSK3b Measured in Biochemical System Using Plate Reader - 2133-10_Inhibitor_Dose_DryPowder_Activity [AID624091_2, Type: other]
View
12
[SID134970447]
CDC2/CycB1 IC50 0.839173Dose responses of selected compounds against GSK3b Measured in Biochemical System Using Plate Reader - 2133-10_Inhibitor_Dose_DryPowder_Activity [AID624091_1, Type: other]
View
13
[SID134970447]
AC50_uM 2.27Human p-Tau and Total Tau ELISA Measured in Cell-Based System Using Plate Reader - 2133-07_Inhibitor_Dose_DryPowder_Activity [AID624057, Type: confirmatory]
View
14
[SID134970447]
Dose responses of selected compounds against GSK3b Measured in Biochemical System Using Plate Reader - 2133-10_Inhibitor_Dose_DryPowder_Activity [AID624091, Type: other]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
View
15
[SID134970447]
GSK3beta Surface Plasmon Resonance (SPR) Assay Measured in Biochemical System Using Microfluidics - 2133-08_Inhibitor_Dose_DryPowder_Activity [AID624108, Type: other]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
View