DURUMOLIDE G (CID 56678384) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Inactive(3)
 
 
Unspecified(2)
 
 
BioAssay Types:
Literature(5)
 
 
 
SAR
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103689172]
 Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as change in beta-actin protein level at 10 uM after 16 hrs by immunoblot analysis [AID420089, Type: Literature]
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2
[SID103689172]
 Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of iNOS protein expression at 10 uM after 16 hrs by immunoblot analysis relative to control [AID420087, Type: Literature]
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3
[SID103689172]
 Antibacterial activity against Salmonella enteritidis ATCC 13076 up to 100 ug/disk after 24 hrs by agar well diffusion method [AID420086, Type: Literature]
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4
[SID103689172]
 Inhibition of HCMV UL76 encoded endonuclease expressed in Escherichia coli BL21 (DE3)-RIL assessed as inhibition of supercoiled double stranded phi X 174 bacteriophage DNA cleavage after 1 hr by agarose gel electrophoresis [AID420085, Type: Literature]
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5
[SID103689172]
 Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of COX2 protein expression at 10 uM after 16 hrs by immunoblot analysis relative to control [AID420088, Type: Literature]
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