GNF-Pf-3267
(CID
56674887
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
1
)
Unspecified(3)
BioActivity Types:
EC50(
2
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 4 Data Row: 4 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103714449
]
Active
EC50
0.1636
NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay [AID
449704
, Type: other]
View
X
Row No.
1
Structure
Substance
SID
103714449
CID
56674887
Outcome
Active
EC50
0.1636 [uM]
BioAssay
NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay
AID
449704
BioAssay type
other
Target
PubMed
Data Table
2
[SID
103714449
]
Unspecified
EC50
1.25
NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay [AID
449703
, Type: other]
View
X
Row No.
2
Structure
Substance
SID
103714449
CID
56674887
Outcome
Unspecified
EC50
1.25 [uM]
BioAssay
NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay
AID
449703
BioAssay type
other
Target
PubMed
Data Table
3
[SID
103714449
]
Unspecified
CC50
10
NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) [AID
449705
, Type: other]
View
X
Row No.
3
Structure
Substance
SID
103714449
CID
56674887
Outcome
Unspecified
CC50
10 [uM]
BioAssay
NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
AID
449705
BioAssay type
other
Target
PubMed
Data Table
4
[SID
103714449
]
Unspecified
NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested. [AID
449706
, Type: other]
View
X
Row No.
4
Structure
Substance
SID
103714449
CID
56674887
Outcome
Unspecified
BioAssay
NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested.
AID
449706
BioAssay type
other
Target
PubMed
Data Table