CHEMBL592603 (CID 56671030) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Unspecified(2)
 
 
Top Targets:
SLC5sbd SGLT1(2)
 
 
 
SLC5sbd SGLT2(2)
 
 
 
BioAssay Types:
Literature(4)
 
 
 
BioActivity Types:
IC50(2)
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4    Data Row: 4   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103723345]
IC50 0.5Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT2 expressed in african green monkey COS1 cells after 30 mins by liquid scintillation counting [AID462408, Type: Literature]Sodium/glucose cotransporter 2 [gi:400337]
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2
[SID103723345]
IC50 4Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT1 expressed in african green monkey COS1 cells after 30 mins by liquid scintillation counting [AID462407, Type: Literature]Sodium/glucose cotransporter 1 [gi:127803]
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3
[SID103723345]
 Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT2 expressed in african green monkey COS1 cells at 50 uM after 30 mins by liquid scintillation counting [AID462410, Type: Literature]Sodium/glucose cotransporter 2 [gi:400337]
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4
[SID103723345]
 Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT1 expressed in african green monkey COS1 cells at 50 uM after 30 mins by liquid scintillation counting [AID462409, Type: Literature]Sodium/glucose cotransporter 1 [gi:127803]
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