CHEMBL1813490 (CID 56666282) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(1)
 
 
Unspecified(13)
 
 
BioAssay Types:
Literature(14)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 14   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134443950]
Free drug level in mouse brain [AID611294, Type: Literature]
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2
[SID134443950]
Toxicity in mouse assessed as increase of spontaneous locomotor activity at 10 to 30 mg/kg, po measured for 5 mins [AID611295, Type: Literature]
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3
[SID134443950]
Antidepressant activity in mouse assessed as reduction of immobility time at 100 mg/kg, po after 60 mins by tail suspension test relative to control [AID611284, Type: Literature]
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4
[SID134443950]
Antidepressant activity in mouse assessed as reduction of immobility time at 30 mg/kg, po after 60 mins by tail suspension test relative to control [AID611283, Type: Literature]
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5
[SID134443950]
Antidepressant activity in mouse assessed as reduction of immobility time at 10 mg/kg, po after 60 mins by tail suspension test relative to control [AID611282, Type: Literature]
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6
[SID134443950]
Antidepressant activity in po dosed mouse assessed as reduction of immobility time after 60 mins by tail suspension test [AID611285, Type: Literature]
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7
[SID134443950]
Plasma concentration in mouse at 3 mg/kg, po [AID611286, Type: Literature]
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8
[SID134443950]
Drug level in mouse brain at 3 mg/kg, po [AID611287, Type: Literature]
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9
[SID134443950]
Plasma concentration in mouse at 10 mg/kg, po [AID611288, Type: Literature]
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10
[SID134443950]
Drug level in mouse brain at 10 mg/kg, po [AID611289, Type: Literature]
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11
[SID134443950]
Plasma concentration in mouse at 30 mg/kg, po [AID611290, Type: Literature]
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12
[SID134443950]
Drug level in mouse brain at 30 mg/kg, po [AID611291, Type: Literature]
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13
[SID134443950]
Ratio of drug level in brain to plasma in mouse at 30 mg/kg, po [AID611292, Type: Literature]
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14
[SID134443950]
Plasma protein binding in mouse [AID611293, Type: Literature]
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