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MLS000543711 (CID 56642946) - Compound BioActivity Data
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BioActivity Outcomes:
Active(26)
 
 
Inactive(696)
 
 
Inconclusive(10)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
 
7TM GPCR Srsx(16)
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
G-alpha(8)
 
 
BioAssay Types:
Screening(498)
 
 
 
 
 
Confirmatory(209)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(146)
 
 
 
 
 
IC50(41)
 
 
 
 
EC50(9)
 
 
 
AC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 660    Data Row: 735   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17408633]
Potency 4.1475Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID17408633]
AC50_uM 8.192MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set4 [AID493102, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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3
[SID17408633]
AC50_uM 8.192MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set2 [AID493177, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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4
[SID17408633]
AC50_uM 8.192MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set3 [AID493073, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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5
[SID17408633]
EC50 11.149High Throughput Screen to Identify Compounds that Suppress the Growth of Cells with a Deletion of the PTEN Tumor Suppressor - Dose Response [AID1047, Type: confirmatory]
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6
[SID17408633]
EC50 12.147High Throughput Screen to Identify Compounds that Suppress the Growth of Human Colon Tumor Cells Lacking Oncogenic Beta Catenin Expression - Dose Response [AID1045, Type: confirmatory]
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7
[SID17408633]
AC50_uM 24.125MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity [AID540346, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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8
[SID17408633]
AC50_uM 24.125MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_CherryPick_Activity_Set2 [AID540335, Type: confirmatory]
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9
[SID17408633]
High Throughput Screen to Identify Compounds that Suppress the Growth of Human Colon Tumor Cells Lacking Oncogenic Beta Catenin Expression [AID818, Type: screening]
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10
[SID17408633]
Counterscreen for antagonists of the orexin 1 receptor (OX1R; HCRTR1): Homogenous time resolved fluorescence (HTRF)-based cell-based assay to identify antagonists of the parental CHO-K1 cell line [AID493232, Type: screening]
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11
[SID17408633]
Fluorescence-based biochemical high throughput confirmation assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID504383, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
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12
[SID17408633]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
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13
[SID17408633]
Leishmania major promastigote HTS [AID1063, Type: screening]
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14
[SID17408633]
High Throughput Screen to Identify Compounds that Suppress the Growth of Cells with a Deletion of the PTEN Tumor Suppressor [AID827, Type: screening]
View
15
[SID17408633]
IC50 uHTS absorbance assay for the identification of compounds that inhibit VHR1. [AID1654, Type: confirmatory]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
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16
[SID17408633]
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity [AID488899, Type: screening]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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17
[SID17408633]
Fluorescence-based biochemical high throughput confirmation assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID504383, Type: screening]troponin C, slow skeletal and cardiac muscles [Homo sapiens] [gi:4507615]
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18
[SID17408633]
Fluorescence-based biochemical high throughput confirmation assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID504383, Type: screening]troponin T, cardiac muscle isoform 3 [Homo sapiens] [gi:48255881]
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19
[SID17408633]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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20
[SID17408633]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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