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BioActivity Data for Compound MLS000550460 (CID 56642945)

BioActivity Outcomes:
Active(3)
 
 
Inactive(672)
 
 
Inconclusive(7)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(41)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
Esterase lipa..(6)
 
 
BioAssay Types:
Screening(463)
 
 
 
 
Confirmatory(197)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(119)
 
 
Toxicity(4)
 
 
Cell-based(130)
 
 
 
Organism-base..(10)
 
 
BioActivity Types:
Potency(143)
 
 
 
 
 
IC50(41)
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 617    Data Row: 683   Total Pages: 35   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14744879]
Potency 0.5221Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID14744879]
Potency 39.8107qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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3
[SID14744879]
High-content cell-based screening for modulators of autophagy [AID463193, Type: screening]microtubule-associated proteins 1A/1B light chain 3A isoform b [Homo sapiens] [gi:31563518]
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4
[SID14744879]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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5
[SID14744879]
Factor XIa 1536 HTS [AID798, Type: screening]coagulation factor XI [Homo sapiens] [gi:180352]
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6
[SID14744879]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
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7
[SID14744879]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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8
[SID14744879]
HTS to Find Inhibitors of Pathogenic Pemphigus Antibodies [AID588358, Type: screening]
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9
[SID14744879]
Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
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10
[SID14744879]
Counterscreen for inhibitors of EBNA-1: fluorescence polarization-based biochemical high throughput primary assay to identify inhibitors of the Epstein-Barr virus-encoded protein, ZTA. [AID2234, Type: screening]BZLF1 [Human herpesvirus 4] [gi:82503229]
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11
[SID14744879]
Luminescence-based primary biochemical high throughput screening assay to identify inhibitors of the Heat Shock Protein 90 (HSP90) [AID1789, Type: screening]HSP90AA1 protein, partial [Homo sapiens] [gi:83318444]
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12
[SID14744879]
uHTS for Small Molecule Inhibitors of Eukaryotic Translation Initiation [AID782, Type: screening]eukaryotic translation initiation factor 4E [Mus musculus] [gi:83627717]
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13
[SID14744879]
High-Throughput Screening for Modulators of Cytosolic Chaperonin Activity [AID651819, Type: screening]TRIC [Homo sapiens] [gi:83758679]
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14
[SID14744879]
TR-FRET-based primary biochemical high-throughput screening assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization [AID1899, Type: screening]core protein, partial [Hepatitis C virus] [gi:83779224]
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15
[SID14744879]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ AGP1_MLPCN. [AID2066, Type: screening]Agp1p [Saccharomyces cerevisiae S288c] [gi:85666113]
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16
[SID14744879]
Potency qHTS Assay for Agonists of the Relaxin Receptor RXFP1 [AID2676, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
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17
[SID14744879]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. [AID1415, Type: screening]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301151]
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18
[SID14744879]
Potency Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
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19
[SID14744879]
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint_HTS_Activity [AID588334, Type: screening]
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20
[SID14744879]
Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Absorbance-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) full deck assay to identify assay artifacts [AID588335, Type: screening]
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