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MLS000047831 (CID 56642925) - Compound BioActivity Data
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BioActivity Outcomes:
Active(13)
 
 
Inactive(778)
 
 
Inconclusive(8)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(29)
 
 
 
7TM GPCR Srsx(21)
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
BioAssay Types:
Screening(559)
 
 
 
 
 
Confirmatory(217)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(145)
 
 
 
 
IC50(52)
 
 
 
EC50(12)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 733    Data Row: 802   Total Pages: 41   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID4242712]
IC50 1.26Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen [AID504723, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] [gi:13399304]
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2
[SID4242712]
IC50_Mean 1.35Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay [AID504724, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3A isoform a [Homo sapiens] [gi:21955158]
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3
[SID4242712]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]muscarinic acetylcholine receptor M5 [Homo sapiens] [gi:7108336]
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4
[SID4242712]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]muscarinic acetylcholine receptor M4 [Homo sapiens] [gi:52426748]
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5
[SID188126304]
Confirmed allosteric antagonists of M1 Muscarinic receptor [AID1053187, Type: other]Muscarinic acetylcholine receptor M1 [gi:113121]
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6
[SID4242712]
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Confirmation Screen [AID677, Type: other]muscarinic acetylcholine receptor M1 [Rattus norvegicus] [gi:18249941]
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7
[SID4242712]
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Dose-Response Assay [AID859, Type: confirmatory]Muscarinic acetylcholine receptor M1 [gi:113121]
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8
[SID4242712]
IC50 uHTS absorbance assay for the identification of compounds that inhibit PHOSPHO1 [AID1565, Type: confirmatory]phosphoethanolamine/phosphocholine phosphatase isoform 1 [Homo sapiens] [gi:219689097]
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9
[SID4242712]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) [AID2014, Type: confirmatory]polyadenylate-binding protein 1 [Homo sapiens] [gi:46367787]
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10
[SID4242712]
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen [AID628, Type: screening]Muscarinic acetylcholine receptor M1 [gi:113121]
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11
[SID4242712]
uHTS identification of APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay [AID493011, Type: screening]DNA dC->dU-editing enzyme APOBEC-3A isoform a [Homo sapiens] [gi:21955158]
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12
[SID4242712]
Single concentration confirmation of uHTS for APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay [AID493151, Type: screening]DNA dC->dU-editing enzyme APOBEC-3A isoform a [Homo sapiens] [gi:21955158]
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13
[SID4242712]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1) [AID588852, Type: screening]muscarinic acetylcholine receptor M1 [Homo sapiens] [gi:37622910]
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14
[SID4242712]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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15
[SID4242712]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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16
[SID4242712]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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17
[SID4242712]
Potency qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
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18
[SID4242712]
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay [AID624204, Type: screening]sentrin-specific protease 1 [Homo sapiens] [gi:7657550]
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19
[SID4242712]
Potency qHTS for Small Molecule Inhibitors of the ERG Ets/DNA interaction [AID624246, Type: confirmatory]transcriptional regulator ERG isoform 3 [Homo sapiens] [gi:343478176]
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20
[SID4242712]
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening] [geneid:3205]
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