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BioActivity Data for Compound MLS000519461 (CID 56642918)

BioActivity Outcomes:
Active(5)
 
 
Inactive(696)
 
 
Inconclusive(25)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(43)
 
 
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
G-alpha(8)
 
 
 
Tryp SPc(7)
 
 
BioAssay Types:
Screening(497)
 
 
 
 
Confirmatory(209)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(117)
 
 
Toxicity(6)
 
 
 
Cell-based(130)
 
 
 
Organism-base..(11)
 
 
BioActivity Types:
Potency(150)
 
 
 
 
 
IC50(45)
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 659    Data Row: 727   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17401926]
Potency 7.9433qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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2
[SID17401926]
uHTS identification of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID602261, Type: screening]fatty acid synthase [Homo sapiens] [gi:41872631]
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3
[SID17401926]
Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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4
[SID17401926]
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity [AID488896, Type: screening]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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5
[SID17401926]
HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]DNA damage-inducible transcript 3 protein [Mus musculus] [gi:160707929]
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6
[SID17401926]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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7
[SID17401926]
Potency 0.0329Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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8
[SID17401926]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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9
[SID17401926]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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10
[SID17401926]
HTS identification of compounds that enhance the binding of CD11b/CD18 to fibrinogen via a luminescence assay. [AID1499, Type: screening]integrin alpha-M isoform 2 precursor [Homo sapiens] [gi:88501734]
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11
[SID17401926]
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay. [AID1497, Type: screening]integrin alpha-M isoform 2 precursor [Homo sapiens] [gi:88501734]
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12
[SID17401926]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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13
[SID17401926]
qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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14
[SID17401926]
qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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15
[SID17401926]
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay. [AID1497, Type: screening]integrin beta-2 precursor [Homo sapiens] [gi:89191865]
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16
[SID17401926]
HTS identification of compounds that enhance the binding of CD11b/CD18 to fibrinogen via a luminescence assay. [AID1499, Type: screening]integrin beta-2 precursor [Homo sapiens] [gi:89191865]
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17
[SID17401926]
Potency qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): qHTS [AID602179, Type: confirmatory]isocitrate dehydrogenase 1, partial [Homo sapiens] [gi:89573979]
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18
[SID17401926]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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19
[SID17401926]
E3 Ligase HTS_1536 [AID1230, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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20
[SID17401926]
High Throughput Screen for Tat Transport Inhibitors Measured in Microorganism System Using Plate Reader - 2093-01_Inhibitor_SinglePoint_HTS_Activity [AID488895, Type: screening]TatABCE protein translocation system subunit [Escherichia coli str. K-12 substr. MG1655] [gi:90111653]
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