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MLS001207393 (CID 56642915) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(524)
 
 
Inconclusive(7)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(15)
 
 
CAP ED(5)
 
 
TRP 2(5)
 
 
RasGEF(4)
 
 
BioAssay Types:
Screening(368)
 
 
Confirmatory(159)
 
 
 
 
 
Literature(5)
 
 
 
BioActivity Types:
Potency(125)
 
 
 
 
 
IC50(28)
 
 
EC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 493    Data Row: 535   Total Pages: 11   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49642303]
Potency 12.5893qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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2
[SID49642303]
Potency 15.8489qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia [AID2451, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-biphosphate Aldolase In Complex With Phosphoglycolohydroxamate [gi:122920737]
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3
[SID49642303]
Potency 79.4328qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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4
[SID49642303]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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5
[SID49642303]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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6
[SID49642303]
Fluorescence-based counterscreen for orexin 1 receptor (OX1R) antagonists: cell-based assay to identify antagonists of the parental CHO cell line [AID463079, Type: screening]
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7
[SID49642303]
uHTS identification of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID463104, Type: screening]
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8
[SID49642303]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
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9
[SID49642303]
Potency qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
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10
[SID49642303]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
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11
[SID49642303]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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12
[SID49642303]
uHTS luminescence assay for the identification of chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation [AID435003, Type: screening]
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13
[SID49642303]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Beta Cell Apoptosis. [AID435005, Type: screening]
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14
[SID49642303]
uHTS luminescence assay for the identification of chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation [AID435022, Type: screening]
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15
[SID49642303]
Counterscreen for inhibitors of AddAB: absorbance-based bacterial cell-based high throughput screening assay to identify inhibitors of bacterial viability [AID449728, Type: screening]
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16
[SID49642303]
IC50 High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
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17
[SID49642303]
uHTS identification of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID449763, Type: screening]
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18
[SID49642303]
Potency qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells [AID2685, Type: confirmatory]
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19
[SID49642303]
A yeast HTS for caloric restriction mimetics that inhibit age-related superoxide [AID2690, Type: screening]
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20
[SID49642303]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
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21
[SID49642303]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Cancer Stem Cells [AID2717, Type: screening]
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22
[SID49642303]
Potency qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Mammalian cellular toxicity [AID2786, Type: confirmatory]
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23
[SID49642303]
IC90 Screen to Identify Novel Compounds That Sensitize Mycobacterium Tuberculosis to Beta-lactam Antibiotics [AID434955, Type: confirmatory]
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24
[SID49642303]
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity [AID2099, Type: screening]
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25
[SID49642303]
Fluorescence Cell-Free Homogeneous Primary HTS to Identify Inhibitors of the RanGTP-Importin-beta complex [AID2216, Type: screening]
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26
[SID49642303]
Potency qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
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27
[SID49642303]
Potency qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21 [AID2289, Type: confirmatory]
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28
[SID49642303]
uHTS identification of small molecules that induce b-cell replication in the MIN-6 cell line [AID2380, Type: screening]
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29
[SID49642303]
IC50 A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) [AID2391, Type: confirmatory]
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30
[SID49642303]
Luminescence-based counterscreen assay for KLF5 inhibitors: cell-based high throughput screening assay to identify cytotoxic compounds using the IEC-6 intestinal epithelial cell line. [AID1825, Type: screening]
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31
[SID49642303]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID1850, Type: confirmatory]
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32
[SID49642303]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID1863, Type: confirmatory]
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33
[SID49642303]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Polyadenylation [AID1875, Type: screening]
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34
[SID49642303]
Luminescence Cell-Based/Microorganism Primary HTS to Identify Inhibitors of T.Cruzi Replication [AID1885, Type: screening]
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35
[SID49642303]
Luminescence Cell-Based Primary HTS to Identify Transcriptional Activators of Hypoxia-Inducible Factor Pathway [AID1910, Type: screening]
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36
[SID49642303]
Potency qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS [AID602332, Type: confirmatory]heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [Homo sapiens] [gi:168984549]
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37
[SID49642303]
Potency qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Giardia lamblia growth inhibition [AID2785, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-biphosphate Aldolase In Complex With Phosphoglycolohydroxamate [gi:122920737]
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38
[SID49642303]
Potency qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Primary screen confirmation [AID2787, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-biphosphate Aldolase In Complex With Phosphoglycolohydroxamate [gi:122920737]
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39
[SID49642303]
Primary cell-based high throughput screening assay to identify inhibitors of kruppel-like factor 5 (KLF5) [AID1700, Type: screening]Kruppel-like factor 5 [Homo sapiens] [gi:124263658]
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40
[SID49642303]
uHTS Luminescent assay for identification of activators of human intestinal alkaline phosphatase [AID2524, Type: screening]Alkaline phosphatase, intestinal [Homo sapiens] [gi:124376142]
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41
[SID49642303]
uHTS Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase [AID2544, Type: screening]Alkaline phosphatase, intestinal [Homo sapiens] [gi:124376142]
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42
[SID49642303]
HTS for developing T Cell Immune Modulators [AID2052, Type: screening]integrin alpha-L isoform 2 precursor [Mus musculus] [gi:124486680]
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43
[SID49642303]
uHTS Luminescent assay for identification of activators of mouse intestinal alkaline phosphatase [AID2805, Type: screening]intestinal alkaline phosphatase precursor [Mus musculus] [gi:124487323]
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44
[SID49642303]
uHTS Luminescent assay for identification of inhibitors of mouse intestinal alkaline phosphatase [AID2806, Type: screening]intestinal alkaline phosphatase precursor [Mus musculus] [gi:124487323]
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45
[SID49642303]
In vivo-based yeast HTS to detect compounds rescuing yeast growth/survival of Plasmodium Falciparum HSP40-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-01_Inhibitor_SinglePoint_HTS_Activity [AID504582, Type: screening]HSP40, subfamily A, putative [Plasmodium falciparum 3D7] [gi:124809271]
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46
[SID49642303]
Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID504621, Type: screening]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
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47
[SID49642303]
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3) [AID1800, Type: screening]NS3 [Hepatitis C virus] [gi:125541954]
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48
[SID49642303]
Fluorescence-based counterscreen assay for HCV NS3 helicase inhibitors: biochemical high-throughput screening assay to identify compounds that cause fluorescent intercalator displacement (FID) [AID1845, Type: screening]NS3 [Hepatitis C virus] [gi:125541954]
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49
[SID49642303]
C. difficile toxins: HTS for inhibitors of TcdB glycohydrolase activity Measured in Biochemical System Using Plate Reader - 7074-01_Inhibitor_SinglePoint_HTS_Activity [AID652162, Type: screening]toxin B [Clostridium difficile 630] [gi:126698238]
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50
[SID49642303]
Potency qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Rabbit FBPA Selectivity [AID2794, Type: confirmatory]fructose-bisphosphate aldolase A [Oryctolagus cuniculus] [gi:126722869]
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