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MLS000682942 (CID 56642910) - Compound BioActivity Data
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BioActivity Outcomes:
Active(12)
 
 
Inactive(687)
 
 
Inconclusive(9)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(17)
 
 
Bcl-2 like(17)
 
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(477)
 
 
 
 
Confirmatory(209)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(142)
 
 
 
 
IC50(38)
 
 
 
EC50(23)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 643    Data Row: 709   Total Pages: 36   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24812748]
EC50_MICROM 36.09Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays [AID1769, Type: confirmatory]glutathione S-transferase, partial [Homo sapiens] [gi:31933]
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2
[SID24812748]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
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3
[SID24812748]
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL. [AID1007, Type: screening]bcl-xL [Homo sapiens] [gi:510901]
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4
[SID24812748]
qHTS Assay for Inhibitors of the Six1/Eya2 Interaction [AID651725, Type: screening]six1 [Homo sapiens] [gi:1246761]
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5
[SID24812748]
ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_SinglePoint_HTS_Activity [AID623870, Type: screening]aryl hydrocarbon receptor nuclear translocator [Homo sapiens] [gi:2702319]
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6
[SID24812748]
qHTS Assay for Inhibitors of the CtBP/E1A Interaction [AID651724, Type: screening]CtBP interacting protein CtIP [Homo sapiens] [gi:1730321]
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7
[SID24812748]
ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_SinglePoint_HTS_Activity [AID623870, Type: screening]transforming acidic coiled-coil-containing protein 3 [Homo sapiens] [gi:5454102]
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8
[SID24812748]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID757, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
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9
[SID24812748]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant [AID764, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
View
10
[SID24812748]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID761, Type: screening]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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11
[SID24812748]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID760, Type: screening]Ras-related protein Rab-2A [gi:46577642]
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12
[SID24812748]
Fluorescence-based biochemical high throughput screening primary assay to identify inhibitors of Crimean-Congo Hemorrhagic Fever (CCHF) viral ovarian tumor domain protease (vOTU): Pep-AMC substrate [AID651958, Type: screening]putative polyprotein [Crimean-Congo hemorrhagic fever virus] [gi:76364066]
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13
[SID24812748]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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14
[SID24812748]
Potency 3.5481qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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15
[SID24812748]
EC50_MICROM 11.83Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. [AID1327, Type: confirmatory]Bcl-2-like protein 10 [gi:23396469]
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16
[SID24812748]
Potency 20.7865Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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17
[SID24812748]
EC50_MICROM 42.84Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) [AID1324, Type: confirmatory]glutathione S-transferase, partial [Homo sapiens] [gi:31933]
View
18
[SID24812748]
Potency 89.1251qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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19
[SID24812748]
Fluorescence polarization-based cell-based primary high throughput screening assay to identify activators of insulin-degrading enzyme (IDE) [AID493087, Type: screening]insulin-degrading enzyme isoform 1 [Homo sapiens] [gi:155969707]
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20
[SID24812748]
Fluorescence polarization-based cell-based primary high throughput screening assay to identify inhibitors of insulin-degrading enzyme (IDE) [AID434962, Type: screening]insulin-degrading enzyme isoform 1 [Homo sapiens] [gi:155969707]
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