Bookmark and Share
MLS000525802 (CID 56642896) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(707)
 
 
Inconclusive(9)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(19)
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
Tryp SPc(9)
 
 
BioAssay Types:
Screening(500)
 
 
 
 
Confirmatory(204)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(148)
 
 
 
 
 
IC50(42)
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 659    Data Row: 720   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14724422]
Potency 19.9526qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
View
2
[SID14724422]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
3
[SID14724422]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
4
[SID14724422]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
5
[SID14724422]
Potency 29.0929qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation [AID540253, Type: confirmatory]GTP-binding nuclear protein Ran [Homo sapiens] [gi:5453555]
View
6
[SID14724422]
Potency 29.0929qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation [AID540253, Type: confirmatory]snurportin-1 [Homo sapiens] [gi:5031833]
View
7
[SID14724422]
Potency 29.0929qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation [AID540253, Type: confirmatory]importin subunit beta-1 isoform 1 [Homo sapiens] [gi:19923142]
View
8
[SID14724422]
Potency 35.4813qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
View
9
[SID14724422]
uHTS determination of small molecule cytotoxicity in a fluorescence assay to identify cystic fibrosis induced NFkb Inhibitors [AID602141, Type: screening]
View
10
[SID14724422]
Full deck counterscreen for positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602247, Type: screening]
View
11
[SID14724422]
Full deck counterscreen for agonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602248, Type: screening]
View
12
[SID14724422]
Full deck counterscreen for antagonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective inhibitors and assay artifacts using the parental CHOK1 cell line [AID602250, Type: screening]
View
13
[SID14724422]
Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Absorbance-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) full deck assay to identify assay artifacts [AID588335, Type: screening]
View
14
[SID14724422]
HTS to Find Inhibitors of Pathogenic Pemphigus Antibodies [AID588358, Type: screening]
View
15
[SID14724422]
Cholera Quorum: HTS for inducers of light production in the absence ofautoinducers using BH1578 (luxS deficient, cqsA deficient) Measured in Microorganism System Using Plate Reader - 2132-01_Agonist_SinglePoint_HTS_Activity [AID588436, Type: screening]
View
16
[SID14724422]
uHTS identification of small molecule modulators of myocardial damage [AID588492, Type: screening]
View
17
[SID14724422]
Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588674, Type: screening]
View
18
[SID14724422]
Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588692, Type: screening]
View
19
[SID14724422]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
20
[SID14724422]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
21
[SID14724422]
Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
View
22
[SID14724422]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening] [geneid:2395]
View
23
[SID14724422]
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint_HTS_Activity [AID588334, Type: screening]
View
24
[SID14724422]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
View
25
[SID14724422]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
View
26
[SID14724422]
IC50 Primary and Confirmatory Screening for Inhibitors of Bacterial Capsule Biogenesis [AID488966, Type: confirmatory]
View
27
[SID14724422]
Potency qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling [AID493014, Type: confirmatory]
View
28
[SID14724422]
Heat Shock Factor-1 (HSF-1) Measured in Cell-Based System Using Plate Reader - 2038-01_Activator_SinglePoint_HTS_Activity [AID504408, Type: screening]
View
29
[SID14724422]
Potency Nrf2 qHTS screen for inhibitors: counterscreen for cytotoxicity [AID504648, Type: confirmatory]
View
30
[SID14724422]
HTS to identify inhibitors of TNF-alpha Induced Cell Death in Jurkat FADD-/- Cells. [AID463075, Type: screening]
View
31
[SID14724422]
Fluorescence-based counterscreen for orexin 1 receptor (OX1R) antagonists: cell-based assay to identify antagonists of the parental CHO cell line [AID463079, Type: screening]
View
32
[SID14724422]
uHTS identification of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID463104, Type: screening]
View
33
[SID14724422]
384-well Z-Lyte format Hck-Nef inhibitor HTS run at the PMLSC [AID463187, Type: screening]
View
34
[SID14724422]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
View
35
[SID14724422]
Potency qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
View
36
[SID14724422]
uHTS luminescence assay for the identification of chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation [AID435003, Type: screening]
View
37
[SID14724422]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Beta Cell Apoptosis. [AID435005, Type: screening]
View
38
[SID14724422]
uHTS luminescence assay for the identification of chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation [AID435022, Type: screening]
View
39
[SID14724422]
Counterscreen for inhibitors of AddAB: absorbance-based bacterial cell-based high throughput screening assay to identify inhibitors of bacterial viability [AID449728, Type: screening]
View
40
[SID14724422]
IC50 High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
View
41
[SID14724422]
uHTS identification of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID449763, Type: screening]
View
42
[SID14724422]
IC50 A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) [AID2391, Type: confirmatory]
View
43
[SID14724422]
Potency qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells [AID2685, Type: confirmatory]
View
44
[SID14724422]
A yeast HTS for caloric restriction mimetics that inhibit age-related superoxide [AID2690, Type: screening]
View
45
[SID14724422]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
View
46
[SID14724422]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Cancer Stem Cells [AID2717, Type: screening]
View
47
[SID14724422]
IC90 Screen to Identify Novel Compounds That Sensitize Mycobacterium Tuberculosis to Beta-lactam Antibiotics [AID434955, Type: confirmatory]
View
48
[SID14724422]
Conc @ Max Fold Increase A high-throughput screen to identify small molecule compounds that augment HSV replication [AID1956, Type: confirmatory]
View
49
[SID14724422]
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity [AID2099, Type: screening]
View
50
[SID14724422]
Fluorescence Cell-Free Homogeneous Primary HTS to Identify Inhibitors of the RanGTP-Importin-beta complex [AID2216, Type: screening]
View