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MLS001242857 (CID 56642851) - Compound BioActivity Data
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BioActivity Outcomes:
Active(18)
 
 
Inactive(459)
 
 
Inconclusive(8)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(35)
 
 
 
CAP ED(5)
 
 
TRP 2(5)
 
 
Esterase lipa..(5)
 
 
ABCC CFTR1(4)
 
 
BioAssay Types:
Screening(355)
 
 
 
Confirmatory(114)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(99)
 
 
 
 
 
IC50(13)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 444    Data Row: 486   Total Pages: 25   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID51089742]
IC50_Mean 9.69Dose response confirmation of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay [AID651693, Type: confirmatory]sentrin-specific protease 1 [Homo sapiens] [gi:7657550]
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2
[SID51089742]
IC50_Mean 19.3Dose response confirmation of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a kinetic FRET assay [AID651697, Type: confirmatory]sentrin-specific protease 1 [Homo sapiens] [gi:7657550]
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3
[SID51089742]
Potency qHTS for Inhibitors of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) [AID652105, Type: confirmatory]Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [gi:18266879]
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4
[SID51089742]
uHTS identification of small molecule inhibitors of Csn-mediated Deneddylation of Cullin-Ring Ligases, vis a fluorescence polarization assay [AID651999, Type: screening]COP9 signalosome complex subunit 5 [Homo sapiens] [gi:38027923]
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5
[SID51089742]
Single Concentration Validation of Csn-Mediated Deneddylation of Cullin-Ring Ligase Using a Fluorescence Polarization Assay [AID720654, Type: other]COP9 signalosome complex subunit 5 [Homo sapiens] [gi:38027923]
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6
[SID51089742]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). [AID1962, Type: screening]likely tRNA 2'-phosphotransferase [Candida albicans SC5314] [gi:68476498]
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7
[SID51089742]
Fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). [AID2149, Type: screening]likely tRNA 2'-phosphotransferase [Candida albicans SC5314] [gi:68476498]
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8
[SID51089742]
Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput primary assay to identify inhibitors of Protein Phosphatase 1 (PP1). [AID2235, Type: screening]serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 3 [Homo sapiens] [gi:56790945]
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9
[SID51089742]
Fluorescence-based biochemical high throughput confirmation assay to identify inhibitors of Protein Phosphatase 1 (PP1) [AID2358, Type: screening]serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 3 [Homo sapiens] [gi:56790945]
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10
[SID51089742]
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay [AID624204, Type: screening]sentrin-specific protease 1 [Homo sapiens] [gi:7657550]
View
11
[SID51089742]
Single concentration confirmation of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay [AID651678, Type: screening]sentrin-specific protease 1 [Homo sapiens] [gi:7657550]
View
12
[SID51089742]
Single concentration confirmation of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a kinetic FRET assay [AID651690, Type: screening]sentrin-specific protease 1 [Homo sapiens] [gi:7657550]
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13
[SID51089742]
Fluorescence polarization-based counterscreen assay for inhibitors of tRNA 2'-phosphotransferase (TPT1): biochemical high throughput screening assay to identify inhibitors of RNAse T1. [AID2153, Type: screening]unnamed protein product [Aspergillus oryzae RIB40] [gi:83774548]
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14
[SID51089742]
HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
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15
[SID51089742]
qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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16
[SID51089742]
qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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17
[SID51089742]
Single concentration validation of Csn-Mediated Deneddylation of Cullin-Ring Ligase Using a Thrombin Fluorescence Polarization Assay [AID720656, Type: other]TPA: prothrombin [Bos taurus] [gi:296479639]
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18
[SID51089742]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463082, Type: screening]platelet-activating factor acetylhydrolase precursor [Homo sapiens] [gi:270133071]
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19
[SID51089742]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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20
[SID51089742]
Potency 17.7828qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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