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Cefixime (CID 56642849) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(70)
 
 
Inactive(408)
 
 
Inconclusive(8)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(14)
 
 
7TM GPCR Srsx(11)
 
 
NB-ARC(6)
 
 
 
Tryp SPc(5)
 
 
 
CAP ED(5)
 
 
BioAssay Types:
Screening(366)
 
 
 
 
Confirmatory(114)
 
 
 
 
 
Literature(3)
 
 
BioActivity Types:
Potency(74)
 
 
 
 
 
IC50(23)
 
 
 
EC50(11)
 
 
 
 
AC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 443    Data Row: 487   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49648844]
EC50 0.06Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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2
[SID49648844]
EC50 0.06Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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3
[SID49648844]
EC50 0.06Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
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4
[SID49648844]
IC50 0.0764Dose Response validation of uHTS RPN11 inhibitor hits using a MMP-2 Fluorescence assay [AID602361, Type: confirmatory]72 kDa type IV collagenase isoform a preproprotein [Homo sapiens] [gi:11342666]
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5
[SID49648844]
Potency 0.1157qHTS for inhibitors of Phosphogylcerate Kinase: Hit Validation Screen [AID686980, Type: confirmatory]phosphoglycerate kinase [Trypanosoma brucei] [gi:115503961]
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6
[SID49648844]
IC50 0.5Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay [AID624317, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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7
[SID49648844]
IC50 1.04Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay [AID602368, Type: confirmatory]PSMD14 protein [Homo sapiens] [gi:16306916]
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8
[SID49648844]
Potency 2.6679qHTS for Inhibitors of Polymerase Iota: Confirmatory Assay for Cherry-picked Compounds [AID720496, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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9
[SID49648844]
Potency 3.3808qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
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10
[SID49648844]
IC50_Mean 4.25Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 [AID651709, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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11
[SID49648844]
EC50_Mean 9.93Dose Response confirmation of uHTS Activators of the Apaf-1 Pathway in Fluorescent format [AID588554, Type: confirmatory]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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12
[SID49648844]
Potency 12.5893qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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13
[SID49648844]
Potency 14.1254HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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14
[SID49648844]
IC50 16.48A counter screen for small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID2384, Type: confirmatory]
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15
[SID49648844]
IC50 17.31A small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID1850, Type: confirmatory]
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16
[SID49648844]
IC50 17.91A screen for inhibitors of the PhoP regulon in Salmonella Typhimurium using a modified counterscreen. [AID1981, Type: confirmatory]
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17
[SID49648844]
IC50 21.035A screen for inhibitors of the PhoP regulon in Salmonella Typhi using a modified counterscreen [AID1985, Type: confirmatory]
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18
[SID49648844]
IC50 22.37A small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID1863, Type: confirmatory]
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19
[SID49648844]
Potency 25.1189qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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20
[SID49648844]
IC50 30.31A Counter Screen to identiry small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID2401, Type: confirmatory]
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21
[SID49648844]
Potency 33.8078qHTS Assay for the Inhibitors of FEN1: Confirmatory Assay for Cherry-picked Compounds [AID720498, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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22
[SID49648844]
AC50_uM 34.772C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_CherryPick_Activity [AID504725, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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23
[SID49648844]
IC50 68.6Dose Response validation of uHTS RPN11 inhibitor hits using a Thrombin Fluorescence Polarization assay [AID602369, Type: confirmatory]TPA: prothrombin [Bos taurus] [gi:296479639]
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24
[SID49648844]
uHTS Fluorescent assay for identification of activators of Apaf-1 [AID489031, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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25
[SID49648844]
Single concentration confirmation of uHTS Fluorescent assay for identification of activators of Apaf-1 [AID504617, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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26
[SID49648844]
C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_SinglePoint_HTS_Activity [AID504423, Type: screening]LANA [Human herpesvirus 8] [gi:312275222]
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27
[SID49648844]
Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput confirmation assay for inhibitors of bacterial viability [AID488956, Type: screening]
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28
[SID49648844]
Counterscreen for inhibitors of AddAB: absorbance-based bacterial cell-based high throughput screening assay to identify inhibitors of bacterial viability [AID449728, Type: screening]
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29
[SID49648844]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
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30
[SID49648844]
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1). [AID720700, Type: screening]Phospholipase C, gamma 1 [Homo sapiens] [gi:223459640]
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31
[SID49648844]
Fluorescence-based biochemical primary high throughput screening assay to identify molecules that bind r(CAG) RNA repeats [AID651821, Type: screening]
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32
[SID49648844]
Counterscreen for inhibitors of RecBCD: Absorbance-based cell-based high throughput assay to identify inhibitors of bacterial viability [AID651983, Type: screening]
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33
[SID49648844]
Fluorescence-based biochemical primary high throughput assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe [AID651800, Type: screening]TCRAV4S1 [Homo sapiens] [gi:2358024]
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34
[SID49648844]
Fluorescence-based biochemical primary high throughput confirmation assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe [AID652036, Type: screening]TCRAV4S1 [Homo sapiens] [gi:2358024]
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35
[SID49648844]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]integrase [Human immunodeficiency virus 1] [gi:2853980]
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36
[SID49648844]
uHTS identification of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay [AID651560, Type: screening]Low molecular weight phosphotyrosine protein phosphatase [gi:1709543]
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37
[SID49648844]
uHTS identification of inhibitors of NadD in a Colorimetric assay [AID602399, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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38
[SID49648844]
Single concentration confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay [AID624309, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
View
39
[SID49648844]
Absorbance-based primary bacterial cell-based high throughput screening assay to identify inhibitors of AddAB recombination protein complex [AID435030, Type: screening]hypothetical protein HP1089 [Helicobacter pylori 26695] [gi:15645703]
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40
[SID49648844]
Absorbance-based bacterial cell-based high throughput confirmation assay for inhibitors of AddAB recombination protein complex [AID488942, Type: screening]hypothetical protein HP1089 [Helicobacter pylori 26695] [gi:15645703]
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41
[SID49648844]
Counterscreen for RECBCD inhibitors: absorbance-based high throughput cell-based assay to identify inhibitors of AddAB recombination protein complex [AID651984, Type: screening]hypothetical protein HP1089 [Helicobacter pylori 26695] [gi:15645703]
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42
[SID49648844]
Absorbance-based primary bacterial cell-based high throughput screening assay to identify inhibitors of AddAB recombination protein complex [AID435030, Type: screening]recombination protein RecB [Helicobacter pylori 26695] [gi:15646160]
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43
[SID49648844]
Absorbance-based bacterial cell-based high throughput confirmation assay for inhibitors of AddAB recombination protein complex [AID488942, Type: screening]recombination protein RecB [Helicobacter pylori 26695] [gi:15646160]
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44
[SID49648844]
Counterscreen for RECBCD inhibitors: absorbance-based high throughput cell-based assay to identify inhibitors of AddAB recombination protein complex [AID651984, Type: screening]recombination protein RecB [Helicobacter pylori 26695] [gi:15646160]
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45
[SID49648844]
MLPCN Streptokinase Expression Inhibition [AID1662, Type: screening]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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46
[SID49648844]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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47
[SID49648844]
uHTS identification of SUMO1-mediated protein-protein interactions [AID602429, Type: screening]SUMO-1 [Homo sapiens] [gi:1762973]
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48
[SID49648844]
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay [AID624204, Type: screening]sentrin-specific protease 1 [Homo sapiens] [gi:7657550]
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49
[SID49648844]
uHTS Colorimetric assay for identification of inhibitors of Scp-1 [AID493091, Type: screening]carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 [Homo sapiens] [gi:10864009]
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50
[SID49648844]
VEID(2) R110 Enzymatic Primary HTS to identify Inhibitors of Caspase 6 Measured in Biochemical System Using Plate Reader - 7052-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID686996, Type: screening]Caspase 6, apoptosis-related cysteine peptidase [Homo sapiens] [gi:13325293]
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