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Cefixime (CID 56642849) - Compound BioActivity Data
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BioActivity Outcomes:
Active(76)
 
 
Inactive(418)
 
 
Inconclusive(8)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(26)
 
 
WD40(6)
 
 
 
CAP ED(5)
 
 
TRP 2(5)
 
 
Esterase lipa..(5)
 
 
BioAssay Types:
Screening(372)
 
 
 
 
Confirmatory(118)
 
 
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(74)
 
 
 
 
 
IC50(27)
 
 
 
EC50(11)
 
 
 
 
AC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 449    Data Row: 503   Total Pages: 26   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49648844]
EC50 0.06Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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2
[SID49648844]
EC50 0.06Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
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3
[SID49648844]
EC50 0.06Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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4
[SID49648844]
IC50 0.0764Dose Response validation of uHTS RPN11 inhibitor hits using a MMP-2 Fluorescence assay [AID602361, Type: confirmatory]72 kDa type IV collagenase isoform a preproprotein [Homo sapiens] [gi:11342666]
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5
[SID49648844]
Potency 0.1157qHTS for inhibitors of Phosphogylcerate Kinase: Hit Validation Screen [AID686980, Type: confirmatory]phosphoglycerate kinase [Trypanosoma brucei brucei strain 927/4 GUTat10.1] [gi:115503961]
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6
[SID49648844]
IC50 0.28715TR-FRET-based biochemical high throughput dose response assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID1053172, Type: confirmatory]integrase, partial [Human immunodeficiency virus 1] [gi:2853980]
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7
[SID49648844]
IC50 0.28715TR-FRET-based biochemical high throughput dose response assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID1053172, Type: confirmatory]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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8
[SID49648844]
IC50 0.5Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay [AID624317, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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9
[SID49648844]
IC50 1.04Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay [AID602368, Type: confirmatory]PSMD14 protein [Homo sapiens] [gi:16306916]
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10
[SID49648844]
Potency 2.6679qHTS for Inhibitors of Polymerase Iota: Confirmatory Assay for Cherry-picked Compounds [AID720496, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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11
[SID49648844]
Potency 3.3808qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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12
[SID49648844]
IC50_Mean 4.25Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 [AID651709, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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13
[SID49648844]
EC50_Mean 9.93Dose Response confirmation of uHTS Activators of the Apaf-1 Pathway in Fluorescent format [AID588554, Type: confirmatory]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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14
[SID49648844]
Potency 12.5893qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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15
[SID49648844]
Potency 14.1254HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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16
[SID49648844]
IC50 16.48A counter screen for small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID2384, Type: confirmatory]
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17
[SID49648844]
IC50 17.31A small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID1850, Type: confirmatory]
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18
[SID49648844]
IC50 17.91A screen for inhibitors of the PhoP regulon in Salmonella Typhimurium using a modified counterscreen. [AID1981, Type: confirmatory]
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19
[SID49648844]
IC50 21.035A screen for inhibitors of the PhoP regulon in Salmonella Typhi using a modified counterscreen [AID1985, Type: confirmatory]
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20
[SID49648844]
IC50 22.37A small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID1863, Type: confirmatory]
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