MLS-0471554.0001 (CID 56639558) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(1)
 
 
Top Targets:
6PGL(2)
 
 
G6PD C(1)
 
 
BioAssay Types:
Confirmatory(3)
 
 
 
BioActivity Types:
IC50(3)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3    Data Row: 3   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134415583]
IC50 11.4SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal kinetic assay utilizing the direct detection of NADPH - Set 3 [AID602425, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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2
[SID134415583]
IC50 15.1SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay - Set 4 [AID602423, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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3
[SID134415583]
IC50 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase using a Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay - Set 4 [AID602424, Type: confirmatory]G6PD gene product [Homo sapiens] [gi:108773793]
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4
[SID134415583]
IC50 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase using a Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay - Set 4 [AID602424, Type: confirmatory]G6PD gene product [Homo sapiens] [gi:108773793]
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