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MLS004257030 (CID 56604880) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(17)
 
 
Inactive(3)
 
 
Top Targets:
Ntn CA(20)
 
 
 
BioAssay Types:
Confirmatory(20)
 
 
 
BioActivity Types:
AC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 20    Data Row: 20   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134356574]
AC50_uM 0.00416Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity_Set2 [AID623985, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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2
[SID134356574]
AC50_uM 0.0111Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity [AID623951, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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3
[SID134356574]
AC50_uM 0.0236Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity_Set4 [AID623993, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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4
[SID134356574]
AC50_uM 0.0254Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity_Set3 [AID623991, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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5
[SID134356574]
AbsAC35_uM 1.45Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624104, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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6
[SID134356574]
AbsAC35_uM 3.67Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity [AID624107, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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7
[SID134356574]
AbsAC35_uM 3.92Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624072, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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8
[SID134356574]
AbsAC35_uM 7.35Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624011, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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9
[SID134356574]
AbsAC35_uM 8.64Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624016, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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10
[SID134356574]
AbsAC35_uM 11.97Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity [AID624105, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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11
[SID134356574]
AbsAC35_uM 12.81Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624073, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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12
[SID134356574]
AbsAC35_uM 16.79Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624020, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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13
[SID134356574]
AbsAC35_uM 19.33Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624106, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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14
[SID134356574]
AbsAC35_uM 19.54Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity [AID624018, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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15
[SID134356574]
AC50_uM 22.9242Whole cell secondary assay to identify compounds reducing the production of iron chelator pyoverdine using Chromeazurol S dye in Pseudomonas Aeruginosa Measured in Whole Organism System Using Imaging - 2091-11_Inhibitor_Dose_DryPowder_Activity [AID624033, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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16
[SID134356574]
AbsAC35_uM 28.97Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624074, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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17
[SID134356574]
AbsAC35_uM 71.14Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624075, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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18
[SID134356574]
AC50_uM Counterscreen measuring mammalian cell toxicity screen in HeLa cells of pyoverdine inhibitors Measured in Cell-Based System Using Plate Reader - 2091-03_Inhibitor_Dose_DryPowder_Activity [AID623950, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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19
[SID134356574]
AC50_uM Counterscreen measuring mammalian cell toxicity screen in HeLa cells of pyoverdine inhibitors Measured in Cell-Based System Using Plate Reader - 2091-03_Inhibitor_Dose_DryPowder_Activity_Set3 [AID623987, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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20
[SID134356574]
AC50_uM Counterscreen measuring mammalian cell toxicity screen in HeLa cells of pyoverdine inhibitors Measured in Cell-Based System Using Plate Reader - 2091-03_Inhibitor_Dose_DryPowder_Activity_Set2 [AID623990, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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