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MLS004257031 (CID 56604851) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(19)
 
 
Inactive(1)
 
 
Top Targets:
Ntn CA(20)
 
 
 
BioAssay Types:
Confirmatory(20)
 
 
 
BioActivity Types:
AC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 20    Data Row: 20   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134356573]
AC50_uM 0.00766Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity_Set4 [AID623993, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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2
[SID134356573]
AC50_uM 0.0156Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity_Set3 [AID623991, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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3
[SID134356573]
AC50_uM 0.0224Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity_Set2 [AID623985, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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4
[SID134356573]
AC50_uM 0.077Fluorescent Biochemical Primary HTS to Identify Inhibitors of P. aeruginosa PvdQ acylase Measured in Biochemical System Using Plate Reader - 2091-02_Inhibitor_Dose_DryPowder_Activity [AID623951, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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5
[SID134356573]
AbsAC35_uM 1.52Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624104, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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6
[SID134356573]
AbsAC35_uM 5.28Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity [AID624107, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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7
[SID134356573]
AbsAC35_uM 6.02Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624072, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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8
[SID134356573]
AbsAC35_uM 7.15Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity [AID624105, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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9
[SID134356573]
AbsAC35_uM 19.57Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624011, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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10
[SID134356573]
AbsAC35_uM 22.33Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624016, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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11
[SID134356573]
AbsAC35_uM 25.87Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624106, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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12
[SID134356573]
AC50_uM 30.6863Whole cell secondary assay to identify compounds reducing the production of iron chelator pyoverdine using Chromeazurol S dye in Pseudomonas Aeruginosa Measured in Whole Organism System Using Imaging - 2091-11_Inhibitor_Dose_DryPowder_Activity [AID624033, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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13
[SID134356573]
AbsAC35_uM 47.46Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624073, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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14
[SID134356573]
AbsAC35_uM 47.46Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK pump mutant mexAB-OprM strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-10_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624074, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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15
[SID134356573]
AbsAC35_uM 68.47Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624020, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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16
[SID134356573]
AbsAC35_uM 101.77Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa (absorbance 405nm) Measured in Whole Organism System Using Plate Reader - 2091-05_Inhibitor_Dose_DryPowder_Activity [AID624018, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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17
[SID134356573]
AC50_uM 110.78Counterscreen measuring mammalian cell toxicity screen in HeLa cells of pyoverdine inhibitors Measured in Cell-Based System Using Plate Reader - 2091-03_Inhibitor_Dose_DryPowder_Activity_Set2 [AID623990, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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18
[SID134356573]
AC50_uM 144.68Counterscreen measuring mammalian cell toxicity screen in HeLa cells of pyoverdine inhibitors Measured in Cell-Based System Using Plate Reader - 2091-03_Inhibitor_Dose_DryPowder_Activity_Set3 [AID623987, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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19
[SID134356573]
AbsAC35_uM 514.84Whole cell secondary assay to determine compounds inducing growth delay in presence of metal chelator in Pseudomonas Aeruginosa PAK strain (absorbance 600nm) Measured in Whole Organism System Using Plate Reader - 2091-08_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624075, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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20
[SID134356573]
AC50_uM Counterscreen measuring mammalian cell toxicity screen in HeLa cells of pyoverdine inhibitors Measured in Cell-Based System Using Plate Reader - 2091-03_Inhibitor_Dose_DryPowder_Activity [AID623950, Type: confirmatory]protein PvdQ [Pseudomonas aeruginosa LESB58] [gi:218891639]
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