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AGN-PC-0BEOMZ (CID 56603524) - Compound BioActivity Data
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BioActivity Outcomes:
Active(87)
 
 
Inactive(323)
 
 
Inconclusive(26)
 
 
Unspecified(13)
 
 
Top Targets:
7TM GPCR Srx(16)
 
 
 
7TM GPCR Srsx(13)
 
 
 
 
Death TRAILR..(12)
 
 
 
 
ABCC CFTR1(9)
 
 
 
 
Peptidase C48(4)
 
 
BioAssay Types:
Screening(320)
 
 
 
 
 
Confirmatory(115)
 
 
 
 
 
Literature(11)
 
 
 
BioActivity Types:
Potency(89)
 
 
 
 
 
IC50(14)
 
 
 
 
 
AC50(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 389    Data Row: 449   Total Pages: 23   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID74373521]
AC50_uM 0.9916ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick [AID463229, Type: confirmatory]
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2
[SID74373521]
AC50_uM 1.333Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
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3
[SID74373521]
AC50_uM 1.69Identification of VIF Inhibitors- ruling Out Cytotoxic Compounds Measured in Cell-Based System Using Imaging - 2108-02_Inhibitor_Dose_CherryPick_Activity [AID652208, Type: confirmatory]Vif [Human immunodeficiency virus 1] [gi:9629361]
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4
[SID74373521]
AC50_uM 1.964Dose Response HTS Screen to Identify Cytotoxic Compounds of HMLE_sh_eGFP [AID463074, Type: confirmatory]
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5
[SID74373521]
Potency 2.31qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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6
[SID74373521]
Potency 2.6855qHTS for antagonists of the Thyroid Stimulation Hormone Receptor: Hit Validation in Primary Screen [AID602292, Type: confirmatory]TSHR protein [Homo sapiens] [gi:118341367]
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7
[SID74373521]
AC50_uM 3.12Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 2144-02_Activator_Dose_CherryPick_Activity [AID720690, Type: confirmatory]
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8
[SID74373521]
AbsAC50_uM 3.66Identification of VIF Inhibitors Measured in Cell-Based System Using Imaging - 2108-01_Inhibitor_Dose_CherryPick_Activity [AID652241, Type: confirmatory]Vif [Human immunodeficiency virus 1] [gi:9629361]
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9
[SID74373521]
AC50_uM 5.241Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Cancer Stem Cells [AID449748, Type: confirmatory]
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10
[SID74373521]
Potency 5.6234qHTS for Inhibitors of Cell Surface uPA Generation [AID540303, Type: confirmatory]urokinase-type plasminogen activator precursor [Mus musculus] [gi:6679377]
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11
[SID74373521]
Potency 5.6234qHTS for Inhibitors of Cell Surface uPA Generation [AID540303, Type: confirmatory]urokinase plasminogen activator surface receptor precursor [Mus musculus] [gi:7242179]
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12
[SID74373521]
Potency 5.6234qHTS for Inhibitors of Cell Surface uPA Generation [AID540303, Type: confirmatory]plasminogen precursor [Mus musculus] [gi:257471003]
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13
[SID74373521]
Potency 5.8048A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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14
[SID74373521]
Potency 7.9433qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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15
[SID74373521]
AC50_uM 8.74Small molecule inhibitors of miR122 Measured in Cell-Based System Using Plate Reader - 2144-01_Activator_Dose_CherryPick_Activity [AID651956, Type: confirmatory]
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16
[SID74373521]
Potency 9.5283qHTS for antagonists of the Thyroid Stimulation Hormone Receptor: Hit Validation in HTRF Activity in a Luteinizing Hormone Receptor Cell Line [AID602293, Type: confirmatory]luteinizing hormone receptor [Homo sapiens] [gi:7704943]
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17
[SID74373521]
Potency 11.2202qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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18
[SID74373521]
Potency 14.581Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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19
[SID74373521]
Potency 16.3601A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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20
[SID74373521]
Potency 25.929qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation [AID540253, Type: confirmatory]importin subunit beta-1 isoform 1 [Homo sapiens] [gi:19923142]
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