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AGN-PC-0BEH27 (CID 56593120) - Compound BioActivity Data
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BioActivity Outcomes:
Active(10)
 
 
Inactive(7)
 
 
Top Targets:
Abhydrolase 2(3)
 
 
Hydrolase 4(2)
 
 
 
Lipase 3(1)
 
 
PLN02442(1)
 
 
Peptidase S9(1)
 
 
BioAssay Types:
Confirmatory(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 17   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99445340]
0.044Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for LYPLA1 and LYPLA2 [AID493110_1, Type: confirmatory]Lypla1 [Mus musculus] [gi:71059731]
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2
[SID99445340]
0.097Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for LYPLA1 and LYPLA2 [AID493110_2, Type: confirmatory]lysophospholipase 2 [Mus musculus] [gi:123122209]
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3
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111_2, Type: other]lysophospholipase 2 [Mus musculus] [gi:123122209]
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4
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111_1, Type: other]Lypla1 [Mus musculus] [gi:71059731]
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5
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: fluorescence-based cell-based inhibition [AID493108_2, Type: other]lysophospholipase 2 [Mus musculus] [gi:123122209]
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6
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: fluorescence-based cell-based inhibition [AID493108_3, Type: other]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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7
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: fluorescence-based cell-based inhibition [AID493108, Type: other]
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8
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for LYPLA1 and LYPLA2 [AID493110, Type: confirmatory]
View
9
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111, Type: other]
View
10
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: fluorescence-based cell-based inhibition [AID493108_1, Type: other]Lypla1 [Mus musculus] [gi:71059731]
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11
[SID99445340]
9Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: absorbance-based cell-based dose response assay to determine cytotoxicity of inhibitor compounds [AID493161_1, Type: confirmatory]
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12
[SID99445340]
27Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: absorbance-based cell-based dose response assay to determine cytotoxicity of inhibitor compounds [AID493161_2, Type: confirmatory]
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13
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: absorbance-based cell-based dose response assay to determine cytotoxicity of inhibitor compounds [AID493161, Type: confirmatory]
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14
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111_3, Type: other]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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15
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111_4, Type: other]Esterase D/formylglutathione hydrolase [Mus musculus] [gi:55777188]
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16
[SID99445340]
Late stage assay provider results from the probe development effort to identify inhibitors of diacylglycerol lipase, beta (DAGLb): fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of overexpressed DAGLb in vitro; triazole urea library [AID602303, Type: other]sn1-specific diacylglycerol lipase beta [Mus musculus] [gi:31559956]
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17
[SID99445340]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111_5, Type: other]Apeh protein, partial [Mus musculus] [gi:20072022]
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