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ML211 (CID 56593118) - Compound BioActivity Data
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BioActivity Outcomes:
Probe(2)
 
 
Active(13)
 
 
Inactive(6)
 
 
Unspecified(5)
 
 
Top Targets:
Abhydrolase 2(6)
 
 
 
 
Esterase lipa..(4)
 
 
 
Lipase 3(1)
 
 
PLN02442(1)
 
 
Peptidase S9(1)
 
 
BioAssay Types:
Confirmatory(7)
 
 
 
Summary(7)
 
 
 
BioActivity Types:
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 26   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99445338]
Summary of probe development efforts to identify inhibitors of lysophospholipase 2 (LYPLA2). [AID2203, Type: summary]lysophospholipase II [Homo sapiens] [gi:4581413]
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2
[SID99445338]
Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202, Type: summary]acyl-protein thioesterase 1 isoform 1 [Homo sapiens] [gi:5453722]
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3
[SID99445338]
IC50 0.01Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for off-target ABHD11 [AID493154, Type: confirmatory]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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4
[SID99445338]
0.017Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for LYPLA1 and LYPLA2 [AID493110_1, Type: confirmatory]Lypla1 [Mus musculus] [gi:71059731]
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5
[SID99445338]
0.03Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for LYPLA1 and LYPLA2 [AID493110_2, Type: confirmatory]lysophospholipase 2 [Mus musculus] [gi:123122209]
View
6
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111_2, Type: other]lysophospholipase 2 [Mus musculus] [gi:123122209]
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7
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: fluorescence-based cell-based inhibition [AID493108_1, Type: other]Lypla1 [Mus musculus] [gi:71059731]
View
8
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: fluorescence-based cell-based inhibition [AID493108_2, Type: other]lysophospholipase 2 [Mus musculus] [gi:123122209]
View
9
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111_1, Type: other]Lypla1 [Mus musculus] [gi:71059731]
View
10
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: LC-MS/MS assay to assess binding of compounds to active site [AID493109, Type: other]LYPLA1 [Homo sapiens] [gi:48146323]
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11
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: fluorescence-based cell-based inhibition [AID493108_3, Type: other]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
View
12
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111_3, Type: other]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
View
13
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: fluorescence-based cell-based inhibition [AID493108, Type: other]
View
14
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for LYPLA1 and LYPLA2 [AID493110, Type: confirmatory]
View
15
[SID99445338]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111, Type: other]
View
16
[SID99445338]
0.01Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_1, Type: summary]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
View
17
[SID99445338]
0.017Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_2, Type: summary]Lypla1 [Mus musculus] [gi:71059731]
View
18
[SID99445338]
0.03Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_3, Type: summary]lysophospholipase 2 [Mus musculus] [gi:123122209]
View
19
[SID99445338]
35Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_4, Type: summary]
View
20
[SID99445338]
50Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_5, Type: summary]
View