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(4-(Hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl)(pyrrolidin-1-yl)methanone (CID 56593032) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(4)
 
 
Top Targets:
Lipase 3(1)
 
 
PLN02442(1)
 
 
PAF-AH p II(1)
 
 
Peptidase S9(1)
 
 
Abhydrolase 2(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2    Data Row: 7   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99445341]
Late stage assay provider results from the probe development effort to identify inhibitors of PAFAH2: Fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) inhibition and selectivity [AID504513_2, Type: other]Apeh protein, partial [Mus musculus] [gi:20072022]
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2
[SID99445341]
Late stage assay provider results from the probe development effort to identify inhibitors of PAFAH2: Fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) inhibition and selectivity [AID504513_3, Type: other]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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3
[SID99445341]
Late stage assay provider results from the probe development effort to identify inhibitors of PAFAH2: Fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) inhibition and selectivity [AID504513_1, Type: other]platelet-activating factor acetylhydrolase 2, cytoplasmic isoform b [Mus musculus] [gi:225579137]
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4
[SID99445341]
Late stage assay provider results from the probe development effort to identify inhibitors of PAFAH2: Fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) inhibition and selectivity [AID504513, Type: other]
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5
[SID99445341]
Late stage assay provider results from the probe development effort to identify inhibitors of PAFAH2: Fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) inhibition and selectivity [AID504513_4, Type: other]Esterase D/formylglutathione hydrolase [Mus musculus] [gi:55777188]
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6
[SID99445341]
Late stage assay provider results from the probe development effort to identify inhibitors of PAFAH2: Fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) inhibition and selectivity [AID504513_5, Type: other]Lypla1 [Mus musculus] [gi:71059731]
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7
[SID99445341]
Late stage assay provider results from the probe development effort to identify inhibitors of diacylglycerol lipase, beta (DAGLb): fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of overexpressed DAGLb in vitro; triazole urea library [AID602303, Type: other]sn1-specific diacylglycerol lipase beta [Mus musculus] [gi:31559956]
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