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BRD-A82372682-001-01-4 (CID 56589421) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(1)
 
 
Top Targets:
STKc GSK3(2)
 
 
STKc CDK5(1)
 
 
CDK5 activato..(1)
 
 
BioAssay Types:
Confirmatory(5)
 
 
 
BioActivity Types:
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134216527]
AC50_uM 7.76e-05PathHunter bCatenin (U2-OS) Measured in Cell-Based System Using Plate Reader - 2133-06_Inhibitor_Dose_DryPowder_Activity [AID624088, Type: confirmatory]
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2
[SID134216527]
AC50_uM 0.614GSK3beta Measured in Biochemical System Using Plate Reader - 2046-01_Inhibitor_Dose_DryPowder_Activity [AID623998, Type: confirmatory]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
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3
[SID134216527]
AC50_uM 39.67CDK5 Measured in Biochemical System Using Plate Reader - 2046-05_Inhibitor_Dose_DryPowder_Activity [AID623999, Type: confirmatory]Cyclin-dependent kinase 5, regulatory subunit 1 (p35) [Homo sapiens] [gi:20072248]
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4
[SID134216527]
AC50_uM 39.67CDK5 Measured in Biochemical System Using Plate Reader - 2046-05_Inhibitor_Dose_DryPowder_Activity [AID623999, Type: confirmatory]CDK5 [Homo sapiens] [gi:48146199]
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5
[SID134216527]
GSK3beta Surface Plasmon Resonance (SPR) Assay Measured in Biochemical System Using Microfluidics - 2133-08_Inhibitor_Dose_DryPowder_Activity [AID624108, Type: other]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
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6
[SID134216527]
AC50_uM TCF/LEF Reporter Assay Measured in Cell-Based System Using Plate Reader - 2133-01_Inhibitor_Dose_DryPowder_Activity [AID624086, Type: confirmatory]
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