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arg-gsk-19 (CID 56589400) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(1)
 
 
Top Targets:
PKc like(2)
 
 
 
STKc CDK5(1)
 
 
CDK5 activato..(1)
 
 
BioAssay Types:
Confirmatory(6)
 
 
BioActivity Types:
AC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 7   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134216536]
AC50_uM 1.12e-05PathHunter bCatenin (U2-OS) Measured in Cell-Based System Using Plate Reader - 2133-06_Inhibitor_Dose_DryPowder_Activity [AID624088, Type: confirmatory]
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2
[SID134216536]
AC50_uM 0.008TCF/LEF Reporter Assay Measured in Cell-Based System Using Plate Reader - 2133-01_Inhibitor_Dose_DryPowder_Activity [AID624086, Type: confirmatory]
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3
[SID134216536]
AC50_uM 0.199GSK3beta Measured in Biochemical System Using Plate Reader - 2046-01_Inhibitor_Dose_DryPowder_Activity [AID623998, Type: confirmatory]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
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4
[SID134216536]
AC50_uM 4.68Human p-Tau and Total Tau ELISA Measured in Cell-Based System Using Plate Reader - 2133-07_Inhibitor_Dose_DryPowder_Activity [AID624057, Type: confirmatory]
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5
[SID134216536]
AC50_uM 10.87CDK5 Measured in Biochemical System Using Plate Reader - 2046-05_Inhibitor_Dose_DryPowder_Activity [AID623999, Type: confirmatory]Cyclin-dependent kinase 5, regulatory subunit 1 (p35) [Homo sapiens] [gi:20072248]
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6
[SID134216536]
AC50_uM 10.87CDK5 Measured in Biochemical System Using Plate Reader - 2046-05_Inhibitor_Dose_DryPowder_Activity [AID623999, Type: confirmatory]CDK5 [Homo sapiens] [gi:48146199]
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7
[SID134216536]
GSK3beta Surface Plasmon Resonance (SPR) Assay Measured in Biochemical System Using Microfluidics - 2133-08_Inhibitor_Dose_DryPowder_Activity [AID624108, Type: other]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
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