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Trifluoperazine (CID 5566) - Compound BioActivity Data
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BioActivity Outcomes:
Active(143)
 
 
Inactive(629)
 
 
Inconclusive(124)
 
 
Unspecified(269)
 
 
Top Targets:
7tm 4(69)
 
 
 
 
 
p450(29)
 
 
 
 
 
ANK(10)
 
 
 
HSD10-like SD..(10)
 
 
 
PLDc mTdp1 2(10)
 
 
 
 
BioAssay Types:
Confirmatory(577)
 
 
 
 
 
Literature(282)
 
 
 
 
 
Screening(238)
 
 
 
 
BioActivity Types:
Potency(373)
 
 
 
 
 
IC50(180)
 
 
 
 
 
Ki(12)
 
 
 
Kd(11)
 
 
AC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 810    Data Row: 1165   Total Pages: 59   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103164917]
Kd 0.000532Compound was tested for its effect on dopamine saturation analysis [AID61331, Type: Literature]
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2
[SID103164917]
Kd 0.00104Compound was tested for its effect on 5-hydroxytryptamine 2 receptor saturation analysis [AID4848, Type: Literature]
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3
[SID103164917]
Ki 0.0022Binding affinity towards dopamine receptor D2 by displacing [3H]spiperone radioligand in rat striatum [AID65908, Type: Literature]
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4
[SID103164917]
Ki 0.0039Binding affinity to emopamil binding protein (unknown origin) [AID723649, Type: Literature]Emopamil-binding protein-like [gi:18202741]
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5
[SID103164917]
Ki 0.0052The compound was tested for its binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [3H]ketanserin radioligand in rat cerebral cortex [AID5307, Type: Literature]
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6
[SID103164917]
Ki 0.008Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand [AID239597, Type: Literature]3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase [gi:17374795]
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7
[SID103164917]
Ki 0.015Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand [AID239347, Type: Literature]
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8
[SID103164917]
IC50 0.016Compound was tested in vitro for its affinity towards rat striatal Dopamine receptor D2 labeled with [3H]- spiperone [AID61326, Type: Literature]
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9
[SID103164917]
Ki 0.0242Inhibition of human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis [AID605819, Type: Literature]
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10
[SID103164917]
Ki 0.0293The compound was tested for its binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]WB-4101 radioligand in rat cerebral cortex [AID35435, Type: Literature]
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11
[SID4252673]
Potency 0.3162qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6 [AID891, Type: confirmatory]cytochrome P450 2D6 isoform 1 [Homo sapiens] [gi:40805836]
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12
[SID103164917]
IC50 0.35In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101 [AID36847, Type: Literature]
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13
[SID103164917]
Ki 0.411Binding affinity towards 5-hydroxytryptamine 1A receptor by displacing [3H]WB-4101 from rat hippocampus [AID4362, Type: Literature]5-hydroxytryptamine receptor 1A [gi:112812]
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14
[SID103164917]
Ki 0.5Affinity for ERG2 of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligand [AID239296, Type: Literature]
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15
[SID103164917]
Kd 0.5Binding affinity to human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis in presence of 10 uM calcium ions [AID605818, Type: Literature]
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16
[SID103164917]
IC50 0.7Inhibitory concentration against hepatitis C virus helicase; range 0.6-0.7 [AID241445, Type: Literature]
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17
[SID103164917]
Kd 0.8Binding affinity to human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis in presence of 7.5 uM calcium ions [AID605817, Type: Literature]
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18
[SID90341087]
Potency 0.8913HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Antagonists [AID488983, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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19
[SID103164917]
Kd 1Binding affinity to human monobromobimane tagged-calmodulin L39C/V91C mutant by fluorescence spectrophotometric analysis in presence of 5 uM calcium ions [AID605816, Type: Literature]
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20
[SID103164917]
Kd 1Binding affinity to calmodulin [AID404335, Type: Literature]
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