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Triclosan (CID 5564) - Compound BioActivity Data
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BioActivity Outcomes:
Active(248)
 
 
Inactive(583)
 
 
Inconclusive(126)
 
 
Unspecified(187)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD ER(16)
 
 
 
7TM GPCR Srsx(15)
 
 
 
7TM GPCR Srx(14)
 
 
 
BioAssay Types:
Literature(373)
 
 
 
 
 
Screening(363)
 
 
 
Confirmatory(338)
 
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(342)
 
 
 
 
 
IC50(82)
 
 
 
 
 
Ki(24)
 
 
EC50(11)
 
 
 
AC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 906    Data Row: 1144   Total Pages: 58   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103222736]
Ki 1.9e-06Inhibition of Plasmodium falciparum ENR in presence of EGCG by dilution assay [AID277593, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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2
[SID103222736]
Ki 5.21e-05Inhibition of Plasmodium falciparum ENR in presence of ECG by dilution assay [AID277595, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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3
[SID103222736]
Ki 0.000109Inhibition of Plasmodium falciparum ENR in presence of EGC by dilution assay [AID277594, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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4
[SID103222736]
Ki 0.000281Inhibition of Plasmodium falciparum ENR in presence of quercetin by dilution assay [AID277596, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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5
[SID103222736]
Ki 0.000798Inhibition of Plasmodium falciparum ENR in presence of butein by dilution assay [AID277597, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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6
[SID103222736]
Ki 0.001Inhibition of Plasmodium falciparum ENR in presence of EGCG [AID277598, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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7
[SID103222736]
IC50 0.005Inhibition of Escherichia coli FabI using 2-dodecenoyl-CoA as substrate at pH 8 [AID751284, Type: Literature]
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8
[SID103222736]
Ki 0.00729Inhibition of Plasmodium falciparum ENR by fluorescence quenching in presence of EGCG [AID277588, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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9
[SID103222736]
Ki 0.008Inhibition of Plasmodium falciparum ENR in presence of ECG [AID277600, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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10
[SID103222736]
Ki 0.00825Inhibition of Plasmodium falciparum ENR in presence of EGC [AID277599, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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11
[SID103222736]
Ki 0.01Inhibition of Plasmodium falciparum ENR in presence of quercetin [AID277601, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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12
[SID103222736]
Ki 0.01372Inhibition of Plasmodium falciparum ENR in presence of butein [AID277602, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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13
[SID103222736]
IC50 0.015Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP [AID741090, Type: Literature]Enoyl-acyl carrier reductase [gi:74837657]
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14
[SID103222736]
IC50 0.015Inhibition of Toxoplasma gondii enoyl acyl-carrier protein reductase [AID753504, Type: Literature]Enoyl-acyl carrier reductase [gi:74837657]
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15
[SID103222736]
IC50 0.02Inhibition of Toxoplasma gondii enoyl reductase [AID509520, Type: Literature]
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16
[SID103222736]
IC50 0.025Inhibition of Staphylococcus aureus FabI using dodecenoyl ACP at pH 7.8 [AID751285, Type: Literature]
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17
[SID103222736]
Ki 0.02831Inhibition of Plasmodium falciparum ENR by fluorescence quenching in presence of ECG [AID277589, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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18
[SID103222736]
Ki 0.03054Inhibition of Plasmodium falciparum ENR by fluorescence quenching in presence of quercetin [AID277591, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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19
[SID103222736]
Ki 0.05Inhibition of Plasmodium falciparum enoyl-acyl carrier protein reductase expressed in Escherichia coli BL21(DE3) by spectrophotometry [AID426408, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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20
[SID170481145]
Ki 0.05Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Analysis Of Plasmodium Falciparum Enoyl- Acyl-Carrier-Protein Reductase With Triclosan [gi:28948861]
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