Bookmark and Share
CHEMBL1950956 (CID 54759170) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(7)
 
 
BioAssay Types:
Literature(7)
 
 
BioActivity Types:
IC50(7)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 7    Data Row: 7   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136925132]
IC50 2Inhibition of His-6 tagged BRD2-RD12 interaction precoupled with biotinylated tetra-acetylated histone H4 expressed in Escherichia coli after 1 hr by TR-FRET assay [AID646023, Type: Literature]
View
2
[SID136925132]
IC50 2Inhibition of His-6 tagged BRD4-RD12 interaction precoupled with biotinylated tetra-acetylated histone H4 expressed in Escherichia coli after 1 hr by TR-FRET assay [AID646025, Type: Literature]
View
3
[SID136925132]
IC50 2.5Inhibition of His-6 tagged BRD3-RD12 interaction precoupled with biotinylated tetra-acetylated histone H4 expressed in Escherichia coli after 1 hr by TR-FRET assay [AID646024, Type: Literature]
View
4
[SID136925132]
IC50 6.3Inhibition of His-6 tagged BRD3 expressed in Escherichia coli after 60 mins by fluorescence anisotropic analysis [AID646021, Type: Literature]
View
5
[SID136925132]
IC50 10Inhibition of His-6 tagged BRD4 expressed in Escherichia coli after 60 mins by fluorescence anisotropic analysis [AID646022, Type: Literature]
View
6
[SID136925132]
IC50 12.6Inhibition of His-6 tagged BRD2 expressed in Escherichia coli after 60 mins by fluorescence anisotropic analysis [AID646020, Type: Literature]
View
7
[SID136925132]
IC50 14Antiinflammatory activity in human PBMC assessed as inhibition of LPS-stimulated IL-6 release after 2 hrs [AID646026, Type: Literature]
View