Bookmark and Share
CHEMBL1831166 (CID 54753271) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(26)
 
 
Inactive(15)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(3)
 
 
 
7TM GPCR Srsx(2)
 
 
ERG2 Sigma1R(1)
 
 
SLC6sbd DAT1(1)
 
 
SLC6sbd NET(1)
 
 
BioAssay Types:
Literature(43)
 
 
 
 
BioActivity Types:
Ki(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 43    Data Row: 43   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134452893]
Ki 0.00745Displacement of [3H]di-o-tolylguanidine from sigma 2 receptor in rat brain membrane after 120 mins [AID619350, Type: Literature]
View
2
[SID134452893]
Ki 0.295Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells [AID619353, Type: Literature]Sodium-dependent serotonin transporter [gi:400630]
View
3
[SID134452893]
Ki 0.544Displacement of [3H]YM-09151-2 from human D3 receptor expressed in CHO cells [AID619357, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
4
[SID134452893]
Ki 0.87Displacement of [3H]YM-09151-2 from human D2 receptor expressed in CHO cells [AID619356, Type: Literature]D(2) dopamine receptor [gi:118206]
View
5
[SID134452893]
Ki 1.27Displacement of [3H]8-OH-DPAT from human 5HT2A receptor expressed in HEK cells [AID619359, Type: Literature]5-hydroxytryptamine receptor 2A [gi:543727]
View
6
[SID134452893]
Ki 1.35Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells [AID619354, Type: Literature]Sodium-dependent noradrenaline transporter [gi:128616]
View
7
[SID134452893]
Ki 1.51Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK cells [AID619358, Type: Literature]5-hydroxytryptamine receptor 1A [gi:231454]
View
8
[SID134452893]
Ki 2.9484Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat brain membrane after 120 mins [AID619349, Type: Literature]Sigma non-opioid intracellular receptor 1 [gi:81882051]
View
9
[SID134452893]
Ki 5Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells [AID619352, Type: Literature]Sodium-dependent dopamine transporter [gi:266667]
View
10
[SID134452893]
Displacement of radioligand from strychnine sensitive glycine receptor assessed as 50% receptor inhibition at 10'-7 M [AID619372, Type: Literature]
View
11
[SID134452893]
Displacement of radioligand from adrenergic alpha1 receptor assessed as 50% receptor inhibition at 10'-5 M [AID619423, Type: Literature]
View
12
[SID134452893]
Displacement of radioligand from adrenergic alpha2 receptor assessed as 50% receptor inhibition at 10'-5 M [AID619424, Type: Literature]
View
13
[SID134452893]
Displacement of radioligand from adrenergic beta1 receptor assessed as 50% receptor inhibition at 10'-5 M [AID619425, Type: Literature]
View
14
[SID134452893]
Displacement of radioligand from cannabinoid CB1 receptor assessed as 50% receptor inhibition at 10'-5 M [AID619426, Type: Literature]
View
15
[SID134452893]
Displacement of radioligand from cannabinoid CB2 receptor assessed as 50% receptor inhibition at 10'-5 M [AID619427, Type: Literature]
View
16
[SID134452893]
Displacement of radioligand from dopamine D4.2 receptor assessed as 50% receptor inhibition at 10'-5 M [AID619428, Type: Literature]
View
17
[SID134452893]
Displacement of radioligand from strychnine sensitive glycine receptor assessed as 50% receptor inhibition at 10'-5 M [AID619429, Type: Literature]
View
18
[SID134452893]
Displacement of radioligand from histamine H1 receptor assessed as 50% receptor inhibition at 10'-5 M [AID619430, Type: Literature]
View
19
[SID134452893]
Displacement of radioligand from histamine H2 receptor assessed as 50% receptor inhibition at 10'-5 M [AID619431, Type: Literature]
View
20
[SID134452893]
Displacement of radioligand from muscarinic M1 receptor assessed as 50% receptor inhibition at 10'-5 M [AID619432, Type: Literature]
View