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MLS000040370 (CID 54750678) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(829)
 
 
Inconclusive(12)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(48)
 
 
alkPPc(16)
 
 
Bcl-2 like(11)
 
 
Tryp SPc(11)
 
 
PTPc(9)
 
 
BioAssay Types:
Screening(565)
 
 
 
 
Confirmatory(254)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(170)
 
 
 
 
 
IC50(49)
 
 
 
EC50(12)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 776    Data Row: 848   Total Pages: 43   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID862023]
Potency 18.3564qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID862023]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) [AID2012, Type: confirmatory]Eukaryotic translation initiation factor 4H [Homo sapiens] [gi:45219878]
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3
[SID862023]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) [AID2014, Type: confirmatory]polyadenylate-binding protein 1 [Homo sapiens] [gi:46367787]
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4
[SID862023]
Primary screen for compounds that activate Insulin promoter activity in TRM-6 cells [AID1296, Type: screening]proinsulin [Homo sapiens] [gi:59036749]
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5
[SID862023]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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6
[SID862023]
Primary biochemical fluorescence polarization-based high throughput screening assay to identify inhibitors of protein arginine methyltransferase 1 (PRMT1) [AID652257, Type: screening]PRMT1 protein, partial [Homo sapiens] [gi:32425330]
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7
[SID862023]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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8
[SID862023]
Potency 8.9125qHTS Assay for Inhibitors of Influenza NS1 Protein Function [AID2326, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/WSN/1933(H1N1))] [gi:194352380]
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9
[SID862023]
Potency 14.1254qHTS of TDP-43 Inhibitors [AID652104, Type: confirmatory]TAR DNA-binding protein 43 [gi:20140568]
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10
[SID862023]
Potency 25.1189qHTS of alpha-syn Inhibitors [AID652106, Type: confirmatory]Alpha-synuclein [gi:586067]
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11
[SID862023]
Potency 67.4555qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
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12
[SID862023]
Potency qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101 [AID493005, Type: confirmatory]tumor susceptibility gene 101 protein [Homo sapiens] [gi:5454140]
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13
[SID862023]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2) [AID651957, Type: screening]nuclear receptor coactivator 2 [Homo sapiens] [gi:5729858]
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14
[SID862023]
IC50 High Throughput Screening Assay for Hsc70 Inhibitors [AID568, Type: confirmatory]heat shock cognate 71 kDa protein isoform 1 [Homo sapiens] [gi:5729877]
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15
[SID862023]
Potency qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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16
[SID862023]
uHTS identification of CXCR6 Inhibitors in a B-arrestin luminescence assay [AID602244, Type: screening]C-X-C chemokine receptor type 6 [Homo sapiens] [gi:5730106]
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17
[SID862023]
uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
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18
[SID862023]
Primary cell-based high-throughput screening assay to identify agonists of Galanin Receptor 2 (GALR2) [AID803, Type: screening]Galanin receptor type 2 [gi:6016094]
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19
[SID862023]
Primary cell-based high-throughput screening assay to identify antagonists of Galanin Receptor 2 (GALR2) [AID828, Type: screening]Galanin receptor type 2 [gi:6016094]
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20
[SID862023]
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 6 (SENP6) [AID2599, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
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