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imazapyr (CID 54738) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(138)
 
 
Inconclusive(6)
 
 
Unspecified(9)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
NR LBD ER(9)
 
 
 
NR LBD AR(9)
 
 
 
NR LBD TR(7)
 
 
NR LBD Fxr(6)
 
 
BioAssay Types:
Confirmatory(97)
 
 
 
Summary(24)
 
 
Literature(13)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(115)
 
 
 
IC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 141    Data Row: 156   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID194182441]
IC50 6.838Inhibition of ALS in ALS-herbicide-susceptible Raphanus raphanistrum WARR7 (wild radish) [AID1112486, Type: Literature]
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2
[SID194182441]
IC50 6.838Inhibition of ALS in ALS-herbicide-susceptible Raphanus raphanistrum WARR33 (wild radish) [AID1112484, Type: Literature]
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3
[SID194182441]
Herbicidal activity against two to three-leaf stage ALS-herbicide-susceptible Raphanus raphanistrum WARR7 (wild radish) assessed as reduction in survival at 50 g/ha measured 3 weeks after compound treatment [AID1112476, Type: Literature]
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4
[SID194182441]
IC50 100Inhibition of ALS Ala122Tyr mutant in ALS-herbicide-resistant Raphanus raphanistrum WARR30 (wild radish) expressing ALS Ala122Tyr mutant [AID1112487, Type: Literature]
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5
[SID194182441]
Resistance index, ratio of GR50 for ALS-herbicide-resistant Raphanus raphanistrum WARR30 (wild radish) expressing ALS Ala122Tyr mutant to GR50 for ALS-herbicide-susceptible Raphanus raphanistrum (wild radish) WARR7 [AID1112488, Type: Literature]
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6
[SID194182441]
Herbicidal activity against two to three leaf stage ALS-herbicide-susceptible Raphanus raphanistrum WARR7 (wild radish) assessed as reduction in dry weight of above-ground biomass measured 3 weeks after compound treatment [AID1112489, Type: Literature]
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7
[SID194182441]
Herbicidal activity against two to three leaf stage ALS-herbicide-resistant Raphanus raphanistrum WARR30 (wild radish) expressing ALS Ala122Tyr mutant assessed as reduction in dry weight of above-ground biomass measured 3 weeks after compound treatment [AID1112490, Type: Literature]
View
8
[SID194182441]
Resistance index, ratio of LD50 for ALS-herbicide-resistant Raphanus raphanistrum WARR30 (wild radish) expressing ALS Ala122Tyr mutant to LD50 for ALS-herbicide-susceptible Raphanus raphanistrum (wild radish) WARR7 [AID1112491, Type: Literature]
View
9
[SID194182441]
Herbicidal activity against two to three leaf stage ALS-herbicide-susceptible Raphanus raphanistrum WARR7 (wild radish) assessed as reduction in survival measured 3 weeks after compound treatment [AID1112492, Type: Literature]
View
10
[SID194182441]
Herbicidal activity against two to three leaf stage ALS-herbicide-resistant Raphanus raphanistrum WARR30 (wild radish) expressing ALS Ala122Tyr mutant assessed as reduction in survival measured 3 weeks after compound treatment [AID1112493, Type: Literature]
View
11
[SID26754627]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
12
[SID194182441]
Resistance index, ratio of I50 for ALS Ala122Tyr mutant in ALS-herbicide-resistant Raphanus raphanistrum WARR30 (wild radish) expressing ALS Ala122Tyr mutant to I50 for ALS-herbicide-susceptible Raphanus raphanistrum (wild radish) [AID1112485, Type: Literature]
View
13
[SID144211318]
Potency-Replicate_1 1.216qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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14
[SID144211318]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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15
[SID144211318]
AR Potency (uM) qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
16
[SID144211318]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
17
[SID92176124]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme BasE [AID485350, Type: screening]enterobactin synthase subunit E [Acinetobacter baumannii ATCC 17978] [gi:126642418]
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18
[SID92176124]
A screen for compounds that inhibit the activity of Staphylococcus aureus DNA helicase [AID485395, Type: other]replicative DNA helicase [Staphylococcus aureus subsp. aureus JH1] [gi:150392496]
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19
[SID99292030]
A screen for compounds that inhibit the activity of Staphylococcus aureus DNA helicase [AID485395, Type: other]replicative DNA helicase [Staphylococcus aureus subsp. aureus JH1] [gi:150392496]
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20
[SID92176124]
A screen for compounds that modulate the activity of the Staphylococcus aureus MgrA protein [AID602314, Type: other]MarR family regulatory protein [Staphylococcus aureus subsp. aureus str. Newman] [gi:151220867]
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