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MLS002154117 (CID 54736625) - Compound BioActivity Data
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BioActivity Outcomes:
Active(105)
 
 
Inactive(283)
 
 
Inconclusive(31)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(34)
 
 
 
 
ANK(5)
 
 
zf-Tim10 DDP(5)
 
 
 
Bcl-2 like(5)
 
 
 
RasGEF(4)
 
 
 
BioAssay Types:
Screening(283)
 
 
 
 
Confirmatory(122)
 
 
 
 
 
Literature(11)
 
 
 
BioActivity Types:
Potency(100)
 
 
 
 
 
IC50(17)
 
 
 
 
AC50(2)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 377    Data Row: 420   Total Pages: 21   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56463155]
Potency 0.0033Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID56463155]
Potency 0.0366qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID56463155]
Potency 0.1458qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID56463155]
Potency 0.2617Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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5
[SID56463155]
Potency 0.92qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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6
[SID56463155]
Potency 1qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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7
[SID56463155]
Potency 1.1582Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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8
[SID56463155]
Potency 1.2995Nrf2 qHTS screen for inhibitors: Nrf2 A549 ARE-Fluc Confirmation Assay for Hit Validation [AID720524, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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9
[SID56463155]
Potency 1.4581qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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10
[SID56463155]
IC50 1.86High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
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11
[SID56463155]
Potency 1.9953qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor, partial [Homo sapiens] [gi:1724069]
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12
[SID56463155]
CC50 2.278A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Mycobacterium Tuberculosis [AID435019, Type: confirmatory]
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13
[SID56463155]
Potency 3.1623qHTS for Inhibitors of Vif-A3F Interactions: qHTS [AID602313, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3F isoform a [Homo sapiens] [gi:22907044]
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14
[SID56463155]
IC50 3.26A High Throughput Confirmatory Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in the absence of Glycerol [AID449764, Type: confirmatory]
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15
[SID56463155]
IC50_Mean 3.92Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent TIM10 yeast counterscreen [AID504542, Type: confirmatory]TPA: protein transporter TIM10 [Saccharomyces cerevisiae S288c] [gi:285809906]
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16
[SID56463155]
Potency 3.9811qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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17
[SID56463155]
AC50_uM 4.394Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
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18
[SID56463155]
EC50 4.95A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhi identified in the primary screen [AID2252, Type: confirmatory]
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19
[SID56463155]
Potency 5.8048Nrf2 qHTS screen for inhibitors: counterscreen for cytotoxicity [AID504648, Type: confirmatory]
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20
[SID56463155]
AC50_uM 5.905HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity [AID540270, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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