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BioActivity Data for Compound NSC603335 (CID 54716343)

BioActivity Outcomes:
Active(7)
 
 
Inactive(372)
 
 
Inconclusive(5)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(23)
 
 
RasGEF(4)
 
 
ABCC CFTR1(4)
 
 
CAP ED(4)
 
 
Troponin(4)
 
 
BioAssay Types:
Screening(213)
 
 
Confirmatory(154)
 
 
 
 
 
Literature(9)
 
 
BioAssay Categories:
In vivo(2)
 
 
Biochemical(79)
 
 
Toxicity(4)
 
 
 
 
Cell-based(73)
 
 
 
Organism-base..(6)
 
 
BioActivity Types:
Potency(75)
 
 
 
 
 
IC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 348    Data Row: 386   Total Pages: 20   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID92763394]
Potency 0.2818qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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2
[SID92763394]
Potency 0.7943qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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3
[SID92763394]
IC50 20.19A Cell-Based Confirmatory Screen for Compounds that Inhibit VEEV, TC-83 [AID588727, Type: confirmatory]
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4
[SID92763394]
CC50 24.9Vero 76 Cytoxicity Assay for VEEV Compounds [AID588719, Type: confirmatory]
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5
[SID483891]
NCI human tumor cell line growth inhibition assay. Data for the K-562 Leukemia cell line [AID121, Type: confirmatory]
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6
[SID483891]
NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line [AID125, Type: confirmatory]
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7
[SID483891]
NCI human tumor cell line growth inhibition assay. Data for the NCI-H460 Non-Small Cell Lung cell line [AID7, Type: confirmatory]
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8
[SID483891]
NCI human tumor cell line growth inhibition assay. Data for the SR Leukemia cell line [AID115, Type: confirmatory]
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9
[SID92763394]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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10
[SID92763394]
Potency 7.0795qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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11
[SID92763394]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
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12
[SID92763394]
Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_SinglePoint_HTS_Activity [AID651661, Type: screening]
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13
[SID92763394]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
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14
[SID92763394]
Fluorescence-based biochemical primary high throughput screening assay to identify molecules that bind r(CAG) RNA repeats [AID651821, Type: screening]
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15
[SID92763394]
Potency qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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16
[SID92763394]
Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based System Using Plate Reader - 7124-01_Inhibitor_SinglePoint_HTS_Activity [AID1053188, Type: screening]
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17
[SID92763394]
High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_SinglePoint_HTS_Activity_Set2 [AID743238, Type: screening]
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18
[SID92763394]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
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19
[SID92763394]
Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition [AID720647, Type: screening]
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20
[SID92763394]
Wnt/Beta-catenin HTS Measured in Cell-Based System Using Plate Reader - 2161-01_Activator_SinglePoint_HTS_Activity [AID743398, Type: screening]
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