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N-cycloheptyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide (CID 54713096) - Compound BioActivity Data
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BioActivity Outcomes:
Active(13)
 
 
Inactive(816)
 
 
Inconclusive(16)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
7TM GPCR Srsx(21)
 
 
alkPPc(16)
 
 
Tryp SPc(13)
 
 
Bcl-2 like(12)
 
 
BioAssay Types:
Screening(553)
 
 
 
 
Confirmatory(254)
 
 
 
 
 
Literature(13)
 
 
BioActivity Types:
Potency(169)
 
 
 
 
 
IC50(49)
 
 
EC50(11)
 
 
AC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 774    Data Row: 846   Total Pages: 43   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID846832]
Potency 1qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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2
[SID846832]
AbsAC40_uM 1.096MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_Dose_CherryPick_Activity [AID540258, Type: confirmatory]
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3
[SID846832]
Potency 2.6855qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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4
[SID846832]
AC50_uM 62.686MITF Act Counter Assay: HeLa CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-08_Activator_Dose_CherryPick_Activity [AID540259, Type: confirmatory]
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5
[SID846832]
Glucocerebrosidase [AID360, Type: confirmatory]Chain A, X-ray Structure Of Human Acid-beta-glucosidase Covalently Bound To Conduritol B Epoxide [gi:66360678]
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6
[SID846832]
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint_HTS_Activity [AID588334, Type: screening]
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7
[SID846832]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
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8
[SID846832]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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9
[SID846832]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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10
[SID846832]
Screen for inhibitors of the SWI/SNF chromatin remodeling complex (esBAF) in mouse embryonic stem cells with Luciferase reporter assay Measured in Cell-Based System Using Plate Reader - 2141-01_Inhibitor_SinglePoint_HTS_Activity [AID602393, Type: screening]transcription activator BRG1 isoform 1 [Mus musculus] [gi:291463269]
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11
[SID846832]
Primary cell-based high throughput screening assay to measure STAT1 activation [AID932, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
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12
[SID846832]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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13
[SID846832]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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14
[SID846832]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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15
[SID846832]
Potency 1.0399qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
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16
[SID846832]
Potency 1.122qHTS of TDP-43 Inhibitors [AID652104, Type: confirmatory]TAR DNA-binding protein 43 [gi:20140568]
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17
[SID846832]
Potency 3.5481qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen [AID720542, Type: confirmatory]apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] [gi:23496270]
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18
[SID846832]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1). [AID1950, Type: screening]EBNA-1 protein [Human herpesvirus 4] [gi:23893623]
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19
[SID846832]
Inhibitors of Epstein-Barr LMP1 inducible NF-kappaB luciferase reporter Measured in Cell-Based System Using Plate Reader - 2122-01_Inhibitor_SinglePoint_HTS_Activity [AID504558, Type: screening]LMP1 [Human herpesvirus 4] [gi:23893668]
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20
[SID846832]
Luminescence Cell-Free Homogenous Primary HTS to Identify Inhibitors of Serine/Threonine Kinase 33 Activity [AID2661, Type: screening]serine/threonine-protein kinase 33 isoform a [Homo sapiens] [gi:23943882]
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