Bookmark and Share
6-chloro-4-hydroxy-3-phenyl-2(1H)-quinolinone (CID 54708959) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(9)
 
 
Inactive(710)
 
 
Inconclusive(6)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(43)
 
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
G-alpha(8)
 
 
 
Tryp SPc(7)
 
 
BioAssay Types:
Screening(498)
 
 
 
 
 
Confirmatory(207)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(150)
 
 
 
 
 
IC50(43)
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 660    Data Row: 727   Total Pages: 37   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17409216]
Potency 9.5283qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
2
[SID17409216]
Primary cell-based high throughput screening assay to measure STAT3 inhibition [AID862, Type: screening]STAT3, partial [Homo sapiens] [gi:13272532]
View
3
[SID17409216]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View
4
[SID17409216]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View
5
[SID17409216]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
View
6
[SID17409216]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
View
7
[SID17409216]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID588726, Type: screening]fructose-bisphosphate aldolase [Mycobacterium tuberculosis H37Rv] [gi:15607504]
View
8
[SID17409216]
Primary cell-based high throughput screening assay to measure STAT1 inhibition [AID920, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
View
9
[SID17409216]
Primary cell based high-throughput screening assay for antagonists of neuropeptide Y receptor Y2 (NPY-Y2) [AID793, Type: screening]neuropeptide Y receptor type 2 [Homo sapiens] [gi:4505447]
View
10
[SID17409216]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
11
[SID17409216]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
12
[SID17409216]
Potency 9.285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
13
[SID17409216]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
14
[SID17409216]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
15
[SID17409216]
Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
View
16
[SID17409216]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening] [geneid:2395]
View
17
[SID17409216]
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint_HTS_Activity [AID588334, Type: screening]
View
18
[SID17409216]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
View
19
[SID17409216]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
View
20
[SID17409216]
IC50 Primary and Confirmatory Screening for Inhibitors of Bacterial Capsule Biogenesis [AID488966, Type: confirmatory]
View