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6-chloro-4-hydroxy-3-phenyl-2(1H)-quinolinone (CID 54708959) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(710)
 
 
Inconclusive(6)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(19)
 
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(498)
 
 
 
 
 
Confirmatory(207)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(150)
 
 
 
 
 
IC50(43)
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 660    Data Row: 727   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17409216]
Potency 9.5283qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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2
[SID17409216]
Primary cell based high-throughput screening assay for antagonists of neuropeptide Y receptor Y2 (NPY-Y2) [AID793, Type: screening]neuropeptide Y receptor type 2 [Homo sapiens] [gi:4505447]
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3
[SID17409216]
Primary cell-based high throughput screening assay to measure STAT3 inhibition [AID862, Type: screening]STAT3, partial [Homo sapiens] [gi:13272532]
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4
[SID17409216]
Primary cell-based high throughput screening assay to measure STAT1 inhibition [AID920, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
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5
[SID17409216]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID588726, Type: screening]fructose-bisphosphate aldolase [Mycobacterium tuberculosis H37Rv] [gi:15607504]
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6
[SID17409216]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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7
[SID17409216]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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8
[SID17409216]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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9
[SID17409216]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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10
[SID17409216]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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11
[SID17409216]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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12
[SID17409216]
Potency 9.285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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13
[SID17409216]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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14
[SID17409216]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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15
[SID17409216]
Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
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16
[SID17409216]
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint_HTS_Activity [AID588334, Type: screening]
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17
[SID17409216]
Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Absorbance-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) full deck assay to identify assay artifacts [AID588335, Type: screening]
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18
[SID17409216]
HTS to Find Inhibitors of Pathogenic Pemphigus Antibodies [AID588358, Type: screening]
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19
[SID17409216]
Cholera Quorum: HTS for inducers of light production in the absence ofautoinducers using BH1578 (luxS deficient, cqsA deficient) Measured in Microorganism System Using Plate Reader - 2132-01_Agonist_SinglePoint_HTS_Activity [AID588436, Type: screening]
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20
[SID17409216]
uHTS identification of small molecule modulators of myocardial damage [AID588492, Type: screening]
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