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Doxycycline (CID 54705095) - Compound BioActivity Data
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BioActivity Outcomes:
Active(54)
 
 
Inactive(501)
 
 
Inconclusive(16)
 
 
Unspecified(4)
 
 
Top Targets:
7tm 4(35)
 
 
 
ZnMc MMP(10)
 
 
 
G-alpha(7)
 
 
 
Tryp SPc(6)
 
 
TRP 2(5)
 
 
BioAssay Types:
Screening(349)
 
 
 
 
Confirmatory(192)
 
 
 
 
 
Literature(27)
 
 
 
 
BioActivity Types:
Potency(131)
 
 
 
 
 
IC50(42)
 
 
 
 
EC50(11)
 
 
 
AC50(2)
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 510    Data Row: 575   Total Pages: 29   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26732641]
Potency 0.7375Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID26732641]
AC50_uM 0.783High Throughput Screen for Tat Transport Inhibitors Measured in Microorganism System Using Plate Reader - 2093-01_Inhibitor_Dose_CherryPick_Activity_Set2 [AID504941, Type: confirmatory]TatABCE protein translocation system subunit [Escherichia coli str. K-12 substr. MG1655] [gi:90111653]
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3
[SID26732641]
IC50 1.54A screen for inhibitors of the PhoP regulon in Salmonella Typhimurium using a modified counterscreen. [AID1981, Type: confirmatory]
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4
[SID26732641]
IC50 1.56A counter screen for small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID2384, Type: confirmatory]
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5
[SID26732641]
IC50 1.971A screen for inhibitors of the PhoP regulon in Salmonella Typhi using a modified counterscreen [AID1985, Type: confirmatory]
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6
[SID26732641]
IC50 2.87A Counter Screen to identiry small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID2401, Type: confirmatory]
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7
[SID26732641]
IC50 3.98A small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID1850, Type: confirmatory]
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8
[SID26732641]
Potency 4.6535Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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9
[SID26732641]
EC50 4.674Luminescence-based Microorganism Dose Response HTS to Identify Inhibitors of E. Coli Growth [AID1959, Type: confirmatory]
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10
[SID26732641]
Potency 5.1735qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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11
[SID26732641]
IC50 6.25A small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID1863, Type: confirmatory]
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12
[SID26732641]
Potency 8.1995qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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13
[SID26732641]
Potency 8.9125qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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14
[SID26732641]
IC50_Mean 10.4Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. [AID504756, Type: confirmatory]cysteine protease ATG4B isoform a [Homo sapiens] [gi:47132611]
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15
[SID26732641]
Potency 12.5893qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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16
[SID26732641]
Potency 19.9526qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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17
[SID26732641]
AC50_uM 20.789Bacterial Growth Inhibition Counterscreen using BacTiter-Glo Measured in Microorganism System Using Plate Reader - 2093-02_Inhibitor_Dose_CherryPick_Activity [AID504843, Type: confirmatory]
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18
[SID26732641]
EC50 27.51A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhimurium identified in the primary screen [AID2253, Type: confirmatory]
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19
[SID26732641]
EC50 28.98A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhi identified in the primary screen [AID2252, Type: confirmatory]
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20
[SID26732641]
EC50 37.937Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 [AID1960, Type: confirmatory]Zinc finger protein mex-5 [gi:55976631]
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