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BioActivity Data for Compound CHEMBL1097558 (CID 54704052)

BioActivity Outcomes:
Active(25)
 
 
Inactive(76)
 
 
Inconclusive(43)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
 
 
NR LBD VDR(5)
 
 
 
NR LBD TR(5)
 
 
 
 
BioAssay Types:
Confirmatory(105)
 
 
 
 
Summary(24)
 
 
 
 
Screening(15)
 
 
 
BioActivity Types:
Potency(110)
 
 
 
 
IC50(10)
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 138    Data Row: 144   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170466575]
IC50 0.53748SNU-C1 viability from Cell TiterGlo-IC50 [AID1117323, Type: confirmatory]
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2
[SID170466575]
IC50 1.02003SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
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3
[SID170466575]
IC50 1.64315Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
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4
[SID170466575]
IC50 2.30868HCT116 viability from Cell TiterGlo-IC50 [AID1117332, Type: confirmatory]
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5
[SID170466575]
IC50 3.78696GSK3B-pretreated HCT116 viability from Cell TiterGlo-IC50 [AID1117339, Type: confirmatory]
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6
[SID170466575]
IC50 4.70275RKO viability from Cell TiterGlo-IC50 [AID1117322, Type: confirmatory]
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7
[SID144205310]
Potency-Replicate_1 5.9557qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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8
[SID144205310]
Potency-Replicate_1 8.4127qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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9
[SID144205310]
Potency-Replicate_1 11.8832qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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10
[SID144205310]
Ratio Potency (uM) 12.533qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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11
[SID144205310]
Ratio Potency (uM) 14.9601qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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12
[SID144205310]
Potency-Replicate_1 21.3138qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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13
[SID144205310]
Ratio Potency (uM) 21.3138qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID144205310]
Potency-Replicate_1 23.7101qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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15
[SID144205310]
AhR Potency (uM) 26.6032qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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16
[SID144205310]
Potency-Replicate_1 29.8493qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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17
[SID144205310]
ER Potency (uM) 29.8493qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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18
[SID144205310]
Potency-Replicate_1 29.8493qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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19
[SID50112923]
Potency 44.6684Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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20
[SID170466575]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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