MolPort-003-100-494 (CID 54703807) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(72)
 
 
Inconclusive(2)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(6)
 
 
 
P53(4)
 
 
Pyr redox dim(3)
 
 
 
7TM GPCR Srw(2)
 
 
Peptidase C1A(2)
 
 
BioAssay Types:
Confirmatory(60)
 
 
 
 
Screening(15)
 
 
 
Literature(1)
 
 
BioActivity Types:
Potency(59)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 74    Data Row: 76   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24408922]
Potency 7.9433qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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2
[SID24408922]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
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3
[SID24408922]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
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4
[SID24408922]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
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5
[SID24408922]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
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6
[SID24408922]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
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7
[SID24408922]
Potency 39.8107qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent) [AID485294, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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8
[SID96143080]
 A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities [AID588519, Type: Literature]Chain A, Poliovirus Polymerase With Gtp [gi:52695378]
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9
[SID24408922]
Potency qHTS of Trypanosoma Brucei Inhibitors [AID624173, Type: confirmatory]hypothetical protein, conserved [Trypanosoma brucei] [gi:62359610]
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10
[SID24408922]
Potency qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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11
[SID24408922]
Potency qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS [AID602332, Type: confirmatory]heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [Homo sapiens] [gi:168984549]
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12
[SID24408922]
Potency qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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13
[SID24408922]
Potency qHTS Assay for Identification of Novel General Anesthetics [AID485281, Type: confirmatory]Chain A, Horse Spleen Apoferritin [gi:254220970]
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14
[SID24408922]
Potency qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent) [AID1476, Type: confirmatory]Chain A, Crystal Structure Of Cruzain Covalently Bound To A Purine Nitrile [gi:281307097]
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15
[SID24408922]
Potency qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent) [AID1478, Type: confirmatory]Chain A, Crystal Structure Of Cruzain Covalently Bound To A Purine Nitrile [gi:281307097]
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16
[SID24408922]
Potency qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM) [AID2528, Type: confirmatory]Bloom syndrome protein [Homo sapiens] [gi:4557365]
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17
[SID24408922]
 Potentiators of Human D1 Dopamine Receptor: qHTS [AID504651, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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18
[SID24408922]
 Potentiators of Human D1 Dopamine Receptor: qHTS [AID504651, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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19
[SID24408922]
 Potentiators of Human D1 Dopamine Receptor: qHTS [AID504651, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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20
[SID24408922]
 Potentiators of Human D1 Dopamine Receptor: qHTS [AID504651, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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21
[SID24408922]
 Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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22
[SID24408922]
 Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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23
[SID24408922]
 Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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24
[SID24408922]
 Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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25
[SID24408922]
 Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS [AID504660, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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26
[SID24408922]
 Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS [AID504660, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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27
[SID24408922]
 Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS [AID504660, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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28
[SID24408922]
 Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS [AID504660, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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29
[SID24408922]
Potency Quantitative High-Throughput Screen for Regulators of Epigenetic Control [AID1865, Type: confirmatory]
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30
[SID24408922]
Potency qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
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31
[SID24408922]
Potency qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
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32
[SID24408922]
Potency qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21 [AID2289, Type: confirmatory]
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33
[SID24408922]
Potency Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
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34
[SID24408922]
Potency Nrf2 qHTS screen for inhibitors: counterscreen for cytotoxicity [AID504648, Type: confirmatory]
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35
[SID24408922]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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36
[SID24408922]
Potency qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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37
[SID24408922]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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38
[SID96143080]
 A screen for compounds that inhibit cell wall-associated teichoic acid synthesis in Staphylococcus aureus [AID463173, Type: screening]
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39
[SID96143080]
 A screen for compounds that inhibit cell wall-associated teichoic acid synthesis in Staphylococcus aureus [AID463173_1, Type: screening]
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40
[SID96143080]
 A screen for compounds that inhibit cell wall-associated teichoic acid synthesis in Staphylococcus aureus [AID463173_2, Type: screening]
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41
[SID24408922]
Potency qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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42
[SID24408922]
Potency qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
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43
[SID24408922]
Potency qHTS of Nrf2 Activators [AID624171, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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44
[SID24408922]
Potency qHTS of Nrf2 Activators [AID624171, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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45
[SID24408922]
Potency qHTS of Nrf2 Activators [AID624171, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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46
[SID24408922]
Potency qHTS of Nrf2 Activators [AID624171, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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47
[SID24408922]
 IkB Signaling [AID445, Type: confirmatory]nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha [Homo sapiens] [gi:10092619]
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48
[SID24408922]
 IkB Signaling [AID445, Type: confirmatory]nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha [Homo sapiens] [gi:10092619]
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49
[SID24408922]
Potency A Quantitative High throughput Screen to Identify Chemical Modulators of PINK1 Expression [AID624263, Type: confirmatory]Parkin [Homo sapiens] [gi:3063388]
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50
[SID24408922]
 HTS Assay for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Primary Screen for Potentiators [AID485347, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
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