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SMR000097186 (CID 54699214) - Compound BioActivity Data
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BioActivity Outcomes:
Active(46)
 
 
Inactive(824)
 
 
Inconclusive(28)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(48)
 
 
 
TRP 2(20)
 
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
 
Tryp SPc(11)
 
 
BioAssay Types:
Screening(606)
 
 
 
 
 
Confirmatory(265)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(170)
 
 
 
 
 
IC50(50)
 
 
 
EC50(13)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 828    Data Row: 900   Total Pages: 45   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7969134]
IC50 1.93Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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2
[SID7969134]
Potency 4.1095qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID7969134]
Potency 5.1735qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID7969134]
EC50 5.956Confirmation dose response assay for compounds that activate transient receptor potential cation channel C4 (TRPC4) [AID434937, Type: confirmatory]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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5
[SID7969134]
IC50 8.45A Cell Based Secondary Assay to Explore Compounds that Modulate Non-Replicating, Drug-tolerant Compounds in Replicating H37Rv TB of Mycobacterium tuberculosis [AID492952, Type: confirmatory]
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6
[SID7969134]
CC50 14.39A Cell Based Secondary Assay to Explore Cytotoxicity in Vero E6 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID492998, Type: confirmatory]
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7
[SID7969134]
CC50 15.421A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Mycobacterium Tuberculosis [AID435019, Type: confirmatory]
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8
[SID7969134]
Potency 18.3564A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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9
[SID7969134]
CC50 20A Cell Based Secondary Assay to Explore Cytotoxicity in HepG2 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID489018, Type: confirmatory]
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10
[SID7969134]
Potency 20.5962Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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11
[SID7969134]
CC50 23.453A Cell Based Secondary Assay to Explore Cytotoxicity in THP-1 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID489025, Type: confirmatory]
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12
[SID7969134]
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A) [AID588511, Type: screening]anoctamin-1 isoform 1 [Mus musculus] [gi:334278898]
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13
[SID7969134]
Re-confirmation assay for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A) [AID652189, Type: screening]anoctamin-1 isoform 1 [Mus musculus] [gi:334278898]
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14
[SID7969134]
Calcium mobilization counter screen for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A) [AID652231, Type: screening]anoctamin-1 isoform 1 [Mus musculus] [gi:334278898]
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15
[SID7969134]
Counter screen for compounds that activate transient receptor potential cation channel C4 (TRPC4). [AID449723, Type: screening]
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16
[SID7969134]
Human Endothelial Cell Proliferation Assay - Dose Response [AID822, Type: confirmatory]
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17
[SID7969134]
Screen for Chemicals that Extend Yeast Lifespan [AID775, Type: screening]
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18
[SID7969134]
Allosteric Modulators of D1 Receptors: Primary Screen [AID641, Type: screening]
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19
[SID7969134]
Human Endothelial Cell Proliferation Assay in 384-well format [AID648, Type: screening]
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20
[SID7969134]
Antimicrobial Assay for E. coli BW25113 ∆tolC::kan - Dose Response [AID617, Type: confirmatory]
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