Bookmark and Share
AE-406/41057142 (CID 54696205) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(3)
 
 
Inactive(705)
 
 
Inconclusive(13)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(16)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(492)
 
 
 
 
 
Confirmatory(214)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(155)
 
 
 
 
IC50(41)
 
 
 
EC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 664    Data Row: 723   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14727975]
EC50 0.332Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole [AID2423, Type: confirmatory]heat shock protein 90 [Candida albicans] [gi:994798]
View
2
[SID14727975]
EC50 2.001Fluorescence Cell-Based Retest of C. albicans Growth in the Presence of Fluconazole [AID2467, Type: confirmatory]
View
3
[SID14727975]
Fluorescence Cell-Based Primary HTS of C.albicans growth in the presence of Fluconazole and compound [AID1979, Type: screening]heat shock protein 90 [Candida albicans] [gi:994798]
View
4
[SID14727975]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
5
[SID14727975]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
6
[SID14727975]
Potency 14.1254qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
7
[SID14727975]
EC50 150Fluorescence Cell-Based Secondary Assay for toxicity in mammalian fibroblasts [AID2327, Type: confirmatory]
View
8
[SID14727975]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID1850, Type: confirmatory]
View
9
[SID14727975]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID1863, Type: confirmatory]
View
10
[SID14727975]
Potency Quantitative High-Throughput Screen for Regulators of Epigenetic Control [AID1865, Type: confirmatory]
View
11
[SID14727975]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Polyadenylation [AID1875, Type: screening]
View
12
[SID14727975]
Luminescence Cell-Based/Microorganism Primary HTS to Identify Inhibitors of T.Cruzi Replication [AID1885, Type: screening]
View
13
[SID14727975]
Luminescence Cell-Based Primary HTS to Identify Transcriptional Activators of Hypoxia-Inducible Factor Pathway [AID1910, Type: screening]
View
14
[SID14727975]
MLPCN Platelet Activation -Dense Granule Release [AID1663, Type: screening]
View
15
[SID14727975]
Profiling compound fluorescence on Avidin Beads with 488 nm excitation and 530 nm emission [AID1775, Type: other]
View
16
[SID14727975]
Profiling compound fluorescence on GSH Beads with 488 nm excitation and 530 nm emission [AID1776, Type: other]
View
17
[SID14727975]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - inhibitors [AID1813, Type: screening]
View
18
[SID14727975]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
View
19
[SID14727975]
Luminescence-based counterscreen assay for KLF5 inhibitors: cell-based high throughput screening assay to identify cytotoxic compounds using the IEC-6 intestinal epithelial cell line. [AID1825, Type: screening]
View
20
[SID14727975]
Counterscreen for inhibitors of Janus kinase 2 mutant JAK2V617F: Cell-based high throughput assay to identify inhibitors of parental Ba/F3 cell viability. [AID1486, Type: screening]
View
21
[SID14727975]
Rml C and D inhibition 384-well mixture HTS [AID1532, Type: screening]
View
22
[SID14727975]
MLPCN Ras selective lethality-BJeLR viability [AID1554, Type: screening]
View
23
[SID14727975]
IC50 A Cell Based Assay for the Identification of Lead Compounds with Anti-Viral Activity Against West Nile Virus [AID1621, Type: confirmatory]
View
24
[SID14727975]
IC50 High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1626, Type: confirmatory]
View
25
[SID14727975]
High Throughput Imaging Assay for Hepatic Lipid Droplet Formation [AID1656, Type: screening]
View
26
[SID14727975]
Chemical Genetic Screen to Identify Inhibitors of Mitochondrial Fusion - Primary Screen [AID1362, Type: screening]
View
27
[SID14727975]
HTS to identify inhibitors of zVAD Induced Cell Death in L929 Cells. [AID1377, Type: screening]
View
28
[SID14727975]
HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules. [AID1381, Type: screening]
View
29
[SID14727975]
Potency Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
View
30
[SID14727975]
EC50 Screen for small molecule probes relevant to Friedreich's ataxia, Single Dose and Dose Response [AID1465, Type: confirmatory]
View
31
[SID14727975]
Potency qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia [AID1477, Type: confirmatory]
View
32
[SID14727975]
NIH Compound Library Profiling: Compound and DTT Dependent Redox Cycling H2O2 Generation. [AID878, Type: screening]
View
33
[SID14727975]
Counter Screen for Luciferase-based Primary Inhibition Assays [AID1006, Type: screening]
View
34
[SID14727975]
Counter Screen for Luciferase-based Primary Stimulation Assays [AID1027, Type: screening]
View
35
[SID14727975]
Leishmania major promastigote HTS [AID1063, Type: screening]
View
36
[SID14727975]
EC50 High Throughput Screen for Inhibitors of ER Stress-induced Cell Death in a 384 well format. [AID1222, Type: confirmatory]
View
37
[SID14727975]
Anti-Viral Drugs Against Arbovirus Infections, a Primary Screen [AID1251, Type: screening]
View
38
[SID14727975]
High Throughput Screen to Identify Compounds that Suppress the Growth of Cells with a Deletion of the PTEN Tumor Suppressor [AID827, Type: screening]
View
39
[SID14727975]
C. albicans biofilm killing [AID834, Type: screening]
View
40
[SID14727975]
Primary HTS assay for chemical modifiers of cytoskeleton assembly [AID836, Type: screening]
View
41
[SID14727975]
Non-Nucleoside Inhibitor of Measles Virus RNA-Dependent RNA Polymerase Complex Activity HTS Single Point (MLSMR Library) [AID841, Type: screening]
View
42
[SID14727975]
Primary HTS assay to asses cytotoxicity for IL-1B stimulated NFkB expression. [AID845, Type: other]
View
43
[SID14727975]
Screen for Chemicals that Inhibit the RAM Network [AID868, Type: screening]
View
44
[SID14727975]
IL-1B Induced NFkB Translocation - Primary Screen [AID796, Type: screening]
View
45
[SID14727975]
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression [AID802, Type: screening]
View
46
[SID14727975]
Screen for Chemicals that Shorten Yeast Lifespan [AID804, Type: screening]
View
47
[SID14727975]
Primary HTS assay for chemical potentiators of TNFalpha stimulated VCAM1 expression [AID808, Type: screening]
View
48
[SID14727975]
High Throughput Screen to Identify Compounds that Suppress the Growth of Human Colon Tumor Cells Lacking Oncogenic Beta Catenin Expression [AID818, Type: screening]
View
49
[SID14727975]
Primary HTS assay for chemical potentiators of IL-1B stimulated NFkB nuclear translocation [AID819, Type: screening]
View
50
[SID14727975]
Potency qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells [AID2685, Type: confirmatory]
View