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BioActivity Data for Compound ASN 15386037 (CID 54693352)

BioActivity Outcomes:
Active(7)
 
 
Inactive(408)
 
 
Inconclusive(12)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(35)
 
 
 
HIF-SF euk(5)
 
 
 
Peptidase C48(4)
 
 
RasGEF(4)
 
 
ABCC CFTR1(4)
 
 
BioAssay Types:
Screening(298)
 
 
 
 
Confirmatory(113)
 
 
 
 
 
Literature(11)
 
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(98)
 
 
 
Toxicity(5)
 
 
Cell-based(83)
 
 
 
Organism-base..(9)
 
 
 
BioActivity Types:
Potency(102)
 
 
 
 
 
IC50(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 389    Data Row: 428   Total Pages: 22   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56422758]
IC50 15.884Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay [AID540297, Type: confirmatory]carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 [Homo sapiens] [gi:10864009]
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2
[SID56422758]
uHTS Colorimetric assay for identification of inhibitors of Scp-1 [AID493091, Type: screening]carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 [Homo sapiens] [gi:10864009]
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3
[SID56422758]
Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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4
[SID56422758]
HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_SinglePoint_HTS [AID485317, Type: screening]FAD-linked sulfhydryl oxidase ALR [Homo sapiens] [gi:54112432]
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5
[SID56422758]
Differential Scanning Fluorimetry (Thermal Shift) Binding Assay for validation of Inhibitors of Scp-1 phosphatase [AID540329, Type: other]carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 [Homo sapiens] [gi:10864009]
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6
[SID56422758]
Single concentration confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay [AID540281, Type: screening]carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 [Homo sapiens] [gi:10864009]
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7
[SID56422758]
Potency qHTS for Inhibitors of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) [AID652105, Type: confirmatory]Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [gi:18266879]
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8
[SID56422758]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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9
[SID56422758]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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10
[SID56422758]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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11
[SID56422758]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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12
[SID56422758]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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13
[SID56422758]
Flow Cytometric HTS Screening for Inhibitors of Lytic Granule Exocytosis with MLPCN Compound Library [AID651702, Type: screening]
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14
[SID56422758]
Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_SinglePoint_HTS_Activity [AID651661, Type: screening]
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15
[SID56422758]
HTS for the detection of C. neoformans cell lysis via adenylate kinase (AK) release Measured in Microorganism System Using Plate Reader - 2162-01_Inhibitor_SinglePoint_HTS_Activity [AID651654, Type: screening]
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16
[SID56422758]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
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17
[SID56422758]
Potency qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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18
[SID56422758]
Potency qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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19
[SID56422758]
Fluorescence-based biochemical primary high throughput screening assay to identify molecules that bind r(CAG) RNA repeats [AID651821, Type: screening]
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20
[SID56422758]
Potency qHTS for Inhibitors of PI5P4K: ADP-Glo counter assay [AID743285, Type: confirmatory]
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