Bookmark and Share
ST077275 (CID 54691677) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(45)
 
 
Inactive(393)
 
 
Inconclusive(21)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(35)
 
 
alkPPc(14)
 
 
 
Bcl-2 like(7)
 
 
 
Tryp SPc(5)
 
 
 
 
NR DBD CAR(4)
 
 
 
BioAssay Types:
Screening(314)
 
 
 
Confirmatory(127)
 
 
 
 
 
Literature(12)
 
 
 
BioActivity Types:
Potency(106)
 
 
 
 
 
IC50(16)
 
 
 
EC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 420    Data Row: 460   Total Pages: 23   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56423669]
Potency 2.3934qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
2
[SID56423669]
IC50 2.413Fluorescence-based biochemical high throughput dose response assay to identify molecules that bind r(CAG) RNA repeats [AID686959, Type: confirmatory]
View
3
[SID56423669]
Potency 4.4668qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
View
4
[SID56423669]
Potency 5.9728qHTS Assay for the Inhibitors of L3MBTL1: Hit Validation [AID540279, Type: confirmatory]lethal(3)malignant brain tumor-like protein 1 isoform I [Homo sapiens] [gi:117938328]
View
5
[SID56423669]
Potency 6.3096qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
View
6
[SID56423669]
Potency 6.3096qHTS for Inhibitors of PI5P4K: Confirmation in Primary Assay [AID743286, Type: confirmatory]Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [gi:18266879]
View
7
[SID56423669]
Potency 8.9125qHTS Assay for the Inhibitors of L3MBTL1 [AID485360, Type: confirmatory]lethal(3)malignant brain tumor-like protein 1 isoform I [Homo sapiens] [gi:117938328]
View
8
[SID56423669]
Potency 8.9125qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
View
9
[SID56423669]
Potency 8.9125Ub-rhodamine 110 based assay for inhibitors Ubiquitin-specific Protease USP2a [AID493170, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
View
10
[SID56423669]
IC50 9.337Counterscreen for molecules that bind rCAG RNA repeats: fluorescent based biochemical dose response assay for inhibitors of the DNA-based (5'CAG/3'GTC) TO-PRO-1 dye complex [AID686960, Type: confirmatory]
View
11
[SID56423669]
Potency 10CHOP2 Reporter Counterscreen Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID493169, Type: confirmatory]enteropeptidase precursor [Homo sapiens] [gi:223942069]
View
12
[SID56423669]
Potency 12.5893qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
View
13
[SID56423669]
Potency 17.7828qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
View
14
[SID56423669]
Potency 18.3564A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
View
15
[SID56423669]
IC50_Mean 18.8Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay [AID488785, Type: confirmatory]intestinal alkaline phosphatase precursor [Mus musculus] [gi:124487323]
View
16
[SID56423669]
Potency 18.8876qHTS for Inhibitors of Polymerase Kappa: Confirmatory Assay for Cherry-picked Compounds [AID720501, Type: Literature]DNA polymerase kappa [Homo sapiens] [gi:7705344]
View
17
[SID56423669]
Potency 23.7781qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
View
18
[SID56423669]
Potency 30.1313qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
View
19
[SID56423669]
Potency 39.8107qHTS for Inhibitors of WRN Helicase [AID651768, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
View
20
[SID56423669]
Potency 44.6684qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
View