MLS000519940 (CID 54690469) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(23)
 
 
Inactive(608)
 
 
Inconclusive(25)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
alkPPc(14)
 
 
Bcl-2 like(10)
 
 
7TM GPCR Srsx(8)
 
 
G-alpha(6)
 
 
BioAssay Types:
Screening(449)
 
 
 
Confirmatory(184)
 
 
 
 
 
Literature(7)
 
 
BioActivity Types:
Potency(130)
 
 
 
 
 
IC50(39)
 
 
EC50(8)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 657    Data Row: 657   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14733170]
Potency 2.2387qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
View
2
[SID14733170]
Potency 2.2387qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
View
3
[SID14733170]
Potency 11.6891Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
4
[SID14733170]
CC50 15.43Vero 76 Cytoxicity Assay for VEEV Compounds [AID588719, Type: confirmatory]
View
5
[SID14733170]
Potency 23.1093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
6
[SID14733170]
Potency 23.1093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
7
[SID14733170]
Potency 23.1093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
8
[SID14733170]
CC50 41.02A Cell Based Secondary Assay To Explore Cytotoxicity of West Nile Virus Anti-Viral Hit Compounds [AID1650, Type: confirmatory]
View
9
[SID14733170]
 High Throughput Screen to Identify Compounds that Suppress the Growth of Human Colon Tumor Cells Lacking Oncogenic Beta Catenin Expression [AID818, Type: screening]
View
10
[SID14733170]
 Screening for Modulators of Post-Golgi Transport, Control Strain [AID738, Type: screening]
View
11
[SID14733170]
 High Throughput Screen to Identify Compounds that Suppress the Growth of Cells with a Deletion of the PTEN Tumor Suppressor [AID827, Type: screening]
View
12
[SID14733170]
 Leishmania major promastigote HTS [AID1063, Type: screening]
View
13
[SID14733170]
 Counter screen for identification of compounds that activate the regulator of G-protein signaling 4 (RGS4): Non-induced cells with the primary screen assay [AID602283, Type: screening]
View
14
[SID14733170]
 uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]EPAS1 gene product [Homo sapiens] [gi:40254439]
View
15
[SID14733170]
 uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]EPAS1 gene product [Homo sapiens] [gi:40254439]
View
16
[SID14733170]
 Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
View
17
[SID14733170]
 Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
View
18
[SID14733170]
 uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
19
[SID14733170]
 uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
20
[SID14733170]
 Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
21
[SID14733170]
 Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
22
[SID14733170]
 Single concentration confirmation of HIF-2a Inhibitors in a HIF-1a counterscreen in human MiAPaCa-2 Cells luciferase reporter assay [AID651589, Type: screening]HIF1A gene product [Homo sapiens] [gi:4504385]
View
23
[SID14733170]
 Single concentration confirmation of HIF-2a Inhibitors in a HIF-1a counterscreen in human MiAPaCa-2 Cells luciferase reporter assay [AID651589, Type: screening]HIF1A gene product [Homo sapiens] [gi:4504385]
View
24
[SID14733170]
 Single concentration confirmation of HIF-2a Inhibitors in a HIF-1a counterscreen in human MiAPaCa-2 Cells luciferase reporter assay [AID651589, Type: screening]HIF1A gene product [Homo sapiens] [gi:4504385]
View
25
[SID14733170]
 Validation assay for identification of compounds that activate the regulator of G-protein signaling 4 (RGS4) [AID602282, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
View
26
[SID14733170]
 Validation assay for identification of compounds that activate the regulator of G-protein signaling 4 (RGS4) [AID602282, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
View
27
[SID14733170]
 Validation assay for identification of compounds that activate the regulator of G-protein signaling 4 (RGS4) [AID602282, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
View
28
[SID14733170]
 Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate regulator of G-protein signaling 4 (RGS4) [AID463111, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
View
29
[SID14733170]
 Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate regulator of G-protein signaling 4 (RGS4) [AID463111, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
View
30
[SID14733170]
 Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate regulator of G-protein signaling 4 (RGS4) [AID463111, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
View
31
[SID14733170]
 uHTS for Small Molecule Inhibitors of Eukaryotic Translation Initiation [AID782, Type: screening]eukaryotic translation initiation factor 4E [Mus musculus] [gi:83627717]
View
32
[SID14733170]
 uHTS for Small Molecule Inhibitors of Eukaryotic Translation Initiation [AID782, Type: screening]eukaryotic translation initiation factor 4E [Mus musculus] [gi:83627717]
View
33
[SID14733170]
 Luminescence-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) [AID602281, Type: screening]ABHD5 gene product [Homo sapiens] [gi:31542303]
View
34
[SID14733170]
 Second counter screen for compounds that modulate the two-pore domain potassium channel (KCNK9) [AID492997, Type: screening]KCNK9 gene product [Homo sapiens] [gi:7706135]
View
35
[SID14733170]
 Confirmatory screen for identification of compounds that inhibit the two-pore domain potassium channel (KCNK9) [AID492992, Type: screening]KCNK9 gene product [Homo sapiens] [gi:7706135]
View
36
[SID14733170]
 Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK9 [AID488922, Type: screening]KCNK9 gene product [Homo sapiens] [gi:7706135]
View
37
[SID14733170]
 Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID588794, Type: screening]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
View
38
[SID14733170]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
39
[SID14733170]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
40
[SID14733170]
Potency 12.5893qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
View
41
[SID14733170]
Potency 19.9526qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
42
[SID14733170]
Potency 19.9526qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
43
[SID14733170]
Potency 19.9526qHTS Assay for Inhibitors of Influenza NS1 Protein Function [AID2326, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/WSN/1933(H1N1))] [gi:194352380]
View
44
[SID14733170]
Potency 31.6228qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy [AID624291, Type: confirmatory]Glycoprotein hormones alpha chain [gi:121312]
View
45
[SID14733170]
Potency 35.4813qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
View
46
[SID14733170]
Potency 35.4813qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
View
47
[SID14733170]
Potency 50.1187qHTS assay for re-activators of p53 using a Luc reporter [AID504706, Type: confirmatory]P53 [Homo sapiens] [gi:23491729]
View
48
[SID14733170]
Potency 50.1187qHTS assay for re-activators of p53 using a Luc reporter [AID504706, Type: confirmatory]P53 [Homo sapiens] [gi:23491729]
View
49
[SID14733170]
Potency 50.1187qHTS assay for re-activators of p53 using a Luc reporter [AID504706, Type: confirmatory]P53 [Homo sapiens] [gi:23491729]
View
50
[SID14733170]
Potency 50.1187qHTS assay for re-activators of p53 using a Luc reporter [AID504706, Type: confirmatory]P53 [Homo sapiens] [gi:23491729]
View