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4-hydroxy-1-methyl-N-(4-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide (CID 54690402) - Compound BioActivity Data
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BioActivity Outcomes:
Active(12)
 
 
Inactive(254)
 
 
Inconclusive(10)
 
 
Top Targets:
alkPPc(12)
 
 
7TM GPCR Srx(10)
 
 
7TM GPCR Srsx(6)
 
 
Tryp SPc(6)
 
 
Pyruvate Kina..(5)
 
 
BioAssay Types:
Confirmatory(161)
 
 
 
 
Screening(105)
 
 
 
Literature(2)
 
 
BioActivity Types:
Potency(97)
 
 
 
 
IC50(34)
 
 
EC50(11)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 260    Data Row: 276   Total Pages: 14   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID844951]
Potency 3.0131qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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2
[SID844951]
Potency 3.5481qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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3
[SID844951]
Potency 3.9811qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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4
[SID844951]
Potency 12.5893qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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5
[SID844951]
Human H69AR Lung Tumor Cell Growth Inhibition Assay - 86K Screen [AID598, Type: screening]
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6
[SID844951]
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
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7
[SID844951]
Primary Cell-based High Throughput Screening assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) [AID522, Type: screening]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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8
[SID844951]
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators [AID639, Type: screening]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
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9
[SID844951]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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10
[SID844951]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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11
[SID844951]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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12
[SID844951]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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13
[SID844951]
Potency 0.5212qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
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14
[SID844951]
Potency 4.1475Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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15
[SID844951]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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16
[SID844951]
Potency Inhibitors of TCP-1 ring complex (TRiC) of Methanococcus maripaludis (MmCpn): qHTS [AID504842, Type: confirmatory]chaperonin-containing TCP-1 beta subunit homolog [Homo sapiens] [gi:4090929]
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17
[SID844951]
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1 [AID540275, Type: screening]transient receptor potential cation channel subfamily V member 1 [Homo sapiens] [gi:74315350]
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18
[SID844951]
HTS Assay for Compounds that Act as Potentiators of the Vanilloid Receptor 1 [AID540277, Type: screening]transient receptor potential cation channel subfamily V member 1 [Homo sapiens] [gi:74315350]
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19
[SID844951]
Potency qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
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20
[SID844951]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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