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AGN-PC-0AAOKC (CID 54689728) - Compound BioActivity Data
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BioActivity Outcomes:
Active(32)
 
 
Inactive(825)
 
 
Inconclusive(23)
 
 
Unspecified(3)
 
 
Top Targets:
7tm 4(48)
 
 
TRP 2(20)
 
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
PTPc(9)
 
 
BioAssay Types:
Screening(579)
 
 
 
 
 
Confirmatory(263)
 
 
 
 
 
Literature(13)
 
 
BioActivity Types:
Potency(165)
 
 
 
 
 
IC50(47)
 
 
 
EC50(22)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 810    Data Row: 883   Total Pages: 45   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID4263924]
EC50 3.419Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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2
[SID4263924]
EC50 3.536Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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3
[SID144220922]
EC50_Mean 5.68SAR analysis of small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format [AID651648, Type: confirmatory]corticotropin-releasing hormone receptor 2 [Homo sapiens] [gi:38349113]
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4
[SID144220922]
EC50_Mean 5.68SAR analysis of small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format [AID651648, Type: confirmatory]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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5
[SID4263924]
EC50_Mean 7.06Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex [AID602473, Type: confirmatory]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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6
[SID4263924]
EC50_Mean 7.06Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex [AID602473, Type: confirmatory]corticotropin-releasing hormone receptor 2 [Homo sapiens] [gi:38349113]
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7
[SID4263924]
Potency 7.9433qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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8
[SID4263924]
Potency 18.3564qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID4263924]
Potency 50.1187qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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10
[SID4263924]
EC50 54.952Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
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11
[SID4263924]
Human Endothelial Cell Proliferation Assay - Dose Response [AID822, Type: confirmatory]
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12
[SID4263924]
Counter screen for compounds that activate transient receptor potential cation channel C4 (TRPC4). [AID449723, Type: screening]
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13
[SID4263924]
Primary Antimicrobial Assay for E. coli BW25113 ∆tolC::kan Protocol for 384-well HTS [AID573, Type: screening]
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14
[SID4263924]
Antimicrobial Assay for E. coli BW25113 ∆tolC::kan - Dose Response [AID617, Type: confirmatory]
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15
[SID4263924]
EC50 Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7K cells) [AID431, Type: confirmatory]
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16
[SID4263924]
Human Endothelial Cell Proliferation Assay in 384-well format [AID648, Type: screening]
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17
[SID4263924]
Screen for Chemicals that Inhibit the RAM Network [AID868, Type: screening]
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18
[SID4263924]
uHTS identification of agonists of the CRF-binding protein and CRF-R2 receptor complex [AID588473, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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19
[SID4263924]
Primary cell-based screen for identification of compounds that activate transient receptor potential cation channel C4 (TRPC4). [AID2237, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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20
[SID4263924]
Second counter screen for compounds that activate transient receptor potential cation channel C4 (TRPC4). [AID434977, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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