PNU 103265 (CID 54688879) - BioAssay Data Summary for Compound
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BioActivity Outcomes:
Active(5)
 
 
Top Targets:
HIV retropeps..(1)
 
 
BioAssay Types:
Literature(5)
 
 
BioActivity Types:
Ki(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179667]
Ki 0.0006Binding affinity against HIV-1 protease [AID160271, Type: Literature]Pol polyprotein [gi:75593047]
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2
[SID103179667]
ED50 1.2Antiviral activity in HIV-1 infected H9 cells [AID78917, Type: Literature]
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3
[SID8030661]
 Literature data for small-molecule inhibitors of HIV-1 Protease [AID417, Type: Literature]Pol polyprotein [gi:75593047]
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4
[SID46392144]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Hiv-1 Protease Triple MutantU103265 COMPLEX [gi:2098357]
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5
[SID103179667]
 Maximum concentration was measured after peroral administration of 5.0 mg/kg of drug in male Dawley rats [AID14092, Type: Literature]
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