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4-Hydroxy-1-methyl-2-quinolone (CID 54686436) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(11)
 
 
Unspecified(3)
 
 
Top Targets:
14-3-3 gamma(1)
 
 
FKBP C(1)
 
 
Flu M2(1)
 
 
G glu transpe..(1)
 
 
HSPA9-like NB..(1)
 
 
BioAssay Types:
Literature(3)
 
 
Screening(2)
 
 
Confirmatory(1)
 
 
BioActivity Types:
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 14   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID160667355]
IC50 100Antikinetoplastid activity against Leishmania donovani MHOM/ET/67/HU3 promastigotes after 3 days incubation at 27 degC under dark condition and 5% CO2 atmosphere by MTT assay [AID659704, Type: Literature]
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2
[SID160667355]
Antikinetoplastid activity against Trypanosoma brucei brucei CMP by drug incubation infectivity test [AID659705, Type: Literature]
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3
[SID160667355]
Cytotoxicity against mouse RAW264.7 cells assessed as cell survival at 100 uM after 24 hrs incubation by trypan blue exclusion method [AID659706, Type: Literature]
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4
[SID11536876]
NMR Based Screening Assay for the substrate binding domain of the chaperone DnaK [AID1033, Type: screening]DnaK protein homolog [Escherichia coli] [gi:216546]
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5
[SID11536876]
NMR assay targeting the ubiquitin-proteasome system to modulate protein folding and degradation [AID1552, Type: other]ubiquitin-conjugating enzyme E2 N [Homo sapiens] [gi:4507793]
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6
[SID92254653]
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
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7
[SID92254653]
A screen for compounds that modulate the activity of the Staphylococcus aureus MgrA protein [AID602314, Type: other]MarR family regulatory protein [Staphylococcus aureus subsp. aureus str. Newman] [gi:151220867]
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8
[SID24308525]
HTS for 14-3-3 protein interaction modulators [AID422, Type: screening]14-3-3 protein gamma [Homo sapiens] [gi:21464101]
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9
[SID11536876]
NMR Based Screening Assay for FKBP12 [AID608, Type: other]peptidyl-prolyl cis-trans isomerase FKBP1A isoform a [Homo sapiens] [gi:17149836]
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10
[SID11536876]
NMR Based Screening Assay for Novel Chemotypes against influenza A virus [AID1549, Type: other]M2 [Influenza A virus (A/Taiwan/4845/1999(H1N1))] [gi:89033149]
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11
[SID11536876]
NMR Based Screening Assay For Novel Chemical Probes Targeting The FRB Domain of mTOR [AID1648, Type: other]Chain A, Nmr Solution Structure Of The Frb Domain Of Mtor [gi:159164579]
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12
[SID95371]
NCI AIDS Antiviral Assay [AID179, Type: confirmatory]
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13
[SID95371]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID256, Type: other]
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14
[SID11536876]
NMR Based Screening Assay for Influenza A RNA Promoter [AID1637, Type: other]
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