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NSC119911 (CID 54686376) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(74)
 
 
Unspecified(8)
 
 
Top Targets:
HSPA1-2 6-8-l..(2)
 
 
Gp dh C(1)
 
 
MH2 SMAD 2 3(1)
 
 
RNase HI euka..(1)
 
 
RNase HI prok..(1)
 
 
BioAssay Types:
Confirmatory(65)
 
 
 
 
Literature(14)
 
 
 
 
Screening(6)
 
 
 
BioActivity Types:
IC50(13)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 91    Data Row: 93   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26514297]
IC50 0.332In Vitro Hsp70 Dose Response Fluorescence Polarization Assay for SAR Study [AID1072, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
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2
[SID26514297]
IC50 2.73In Vitro Hsc70 Dose Response Fluorescence Polarization Assay [AID1193, Type: confirmatory]heat shock cognate 71 kDa protein isoform 2 [Homo sapiens] [gi:24234686]
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3
[SID26514297]
IC50 2.73In Vitro Hsc70 Dose Response Fluorescence Polarization Assay [AID1193, Type: confirmatory]heat shock cognate 71 kDa protein isoform 1 [Homo sapiens] [gi:5729877]
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4
[SID103566040]
IC50 11Inhibition of beta-lactamase AmpC [AID318865, Type: Literature]
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5
[SID26514297]
IC50 15.8GAPDH Dose Response Colorimetric Assay [AID1227, Type: confirmatory]glyceraldehyde-3-phosphate dehydrogenase isoform 1 [Homo sapiens] [gi:7669492]
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6
[SID103566040]
IC50 20Inhibition of malate dehydrogenase [AID318869, Type: Literature]
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7
[SID103566040]
IC50 24Inhibition of chymotrypsin [AID318867, Type: Literature]
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8
[SID103650864]
IC50 47Inhibition of Escherichia coli MurD assessed as blockade of addition of D-[14C]Glu to UDP-MurNAc-L-Ala [AID393934, Type: Literature]
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9
[SID8139587]
human RNase H Inhibition [AID366, Type: screening]ribonuclease H1 isoform 1 precursor [Homo sapiens] [gi:21359816]
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10
[SID8139587]
E. coli RNase H Inhibition [AID365, Type: screening]Ribonuclease HI [gi:67472286]
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11
[SID8139587]
HIV-2 RNase H Inhibition [AID367, Type: screening]Chain A, Crystal Structure Of Hiv-2 Reverse Transcriptase [gi:24987805]
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12
[SID103566040]
IC50 77Inhibition of malate dehydrogenase in presence of 0.1% Triton X-100 [AID318870, Type: Literature]
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13
[SID103566040]
IC50 95Inhibition of cruzain [AID318871, Type: Literature]
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14
[SID103566040]
IC50 106Inhibition of cruzain in presence of 0.01% Triton X-100 [AID318872, Type: Literature]
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15
[SID103566040]
IC50 600Inhibition of chymotrypsin in presence of 0.1% Triton X-100 [AID318868, Type: Literature]
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16
[SID103566040]
IC50 600Inhibition of beta-lactamase AmpC in presence of 0.1% Triton X-100 [AID318866, Type: Literature]
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17
[SID435970]
NCI AIDS Antiviral Assay [AID179, Type: confirmatory]
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18
[SID103650864]
Inhibition of Escherichia coli MurD assessed as residual activity at 250 uM by malachite green assay [AID393764, Type: Literature]
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19
[SID414516]
NCI AIDS Antiviral Assay [AID179, Type: confirmatory]
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20
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the 786-0 Renal cell line [AID137, Type: confirmatory]
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21
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line [AID139, Type: confirmatory]
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22
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the TK-10 Renal cell line [AID141, Type: confirmatory]
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23
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line [AID143, Type: confirmatory]
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24
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line [AID145, Type: confirmatory]
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25
[SID414516]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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26
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the K-562 Leukemia cell line [AID121, Type: confirmatory]
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27
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the MOLT-4 Leukemia cell line [AID123, Type: confirmatory]
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28
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line [AID125, Type: confirmatory]
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29
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the A498 Renal cell line [AID129, Type: confirmatory]
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30
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the CAKI-1 Renal cell line [AID131, Type: confirmatory]
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31
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the RXF 393 Renal cell line [AID133, Type: confirmatory]
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32
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-4 Ovarian cell line [AID105, Type: confirmatory]
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33
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-5 Ovarian cell line [AID107, Type: confirmatory]
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34
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-8 Ovarian cell line [AID109, Type: confirmatory]
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35
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the RPMI-8226 Leukemia cell line [AID113, Type: confirmatory]
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36
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the SR Leukemia cell line [AID115, Type: confirmatory]
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37
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the CCRF-CEM Leukemia cell line [AID119, Type: confirmatory]
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38
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the NCI/ADR-RES Breast cell line [AID93, Type: confirmatory]
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39
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-231/ATCC Breast cell line [AID95, Type: confirmatory]
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40
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the HS 578T Breast cell line [AID97, Type: confirmatory]
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41
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-3 Ovarian cell line [AID99, Type: confirmatory]
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42
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Ovarian cell line [AID101, Type: confirmatory]
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43
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the SK-OV-3 Ovarian cell line [AID103, Type: confirmatory]
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44
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the SW-620 Colon cell line [AID81, Type: confirmatory]
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45
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the MCF7 Breast cell line [AID83, Type: confirmatory]
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46
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-435 Breast cell line [AID85, Type: confirmatory]
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47
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line [AID87, Type: confirmatory]
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48
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the BT-549 Breast cell line [AID89, Type: confirmatory]
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49
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the T-47D Breast cell line [AID91, Type: confirmatory]
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50
[SID414516]
NCI human tumor cell line growth inhibition assay. Data for the HT29 Colon cell line [AID65, Type: confirmatory]
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