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Oxytetracycline (CID 54680782) - Compound BioActivity Data
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BioActivity Outcomes:
Active(82)
 
 
Inactive(410)
 
 
Inconclusive(128)
 
 
Unspecified(19)
 
 
Top Targets:
NR LBD PPAR(28)
 
 
 
NR LBD AR(25)
 
 
 
NR LBD ER(25)
 
 
 
 
NR LBD TR(17)
 
 
NR LBD GR(16)
 
 
 
BioAssay Types:
Confirmatory(384)
 
 
 
 
Literature(70)
 
 
 
 
 
Summary(63)
 
 
 
Screening(5)
 
 
BioActivity Types:
Potency(396)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 325    Data Row: 639   Total Pages: 13   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389774]
Potency 3.3587qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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2
[SID17389774]
Potency 3.5481qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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3
[SID17389774]
Potency 3.7933Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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4
[SID17389774]
Potency 6.3096qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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5
[SID17389774]
Potency 6.3096qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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6
[SID17389774]
Potency 7.0795qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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7
[SID17389774]
Potency 10qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase 1 [gi:44888968]
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8
[SID17389774]
Potency 13.4591Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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9
[SID144204660]
Potency 18.8375qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID17389774]
Potency 28.1838qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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11
[SID26757862]
Potency 35.4813qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID144210918]
Potency-Replicate_1 42.223qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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13
[SID17389774]
Potency 44.6684qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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14
[SID144210918]
Potency-Replicate_1 47.375qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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15
[SID144210918]
Potency-Replicate_1 47.375qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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16
[SID17389774]
Potency 50.1187Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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17
[SID144209048]
Potency-Replicate_1 54.3719qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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18
[SID144209048]
Potency-Replicate_1 54.3719qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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19
[SID144209048]
Potency-Replicate_1 68.4501qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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20
[SID17389774]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_26, Type: Literature]
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21
[SID8149465]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH20) [AID1606, Type: other]
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22
[SID8149465]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH016) [AID1608, Type: other]
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23
[SID8149465]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH08) [AID1609, Type: other]
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24
[SID8149465]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells [AID1610, Type: other]
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25
[SID8149465]
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells (LDH100) [AID1596, Type: other]
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26
[SID8149465]
Cellular toxicity caused by inducible expressing of N-terminal huntingtin with expanded ployglutamine repeat (Htt-N63-148Q) in PC12 cells (ROSShtt) [AID1590, Type: other]
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27
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L2 [gi:42560210]
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28
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L3 [gi:42560216]
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29
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L30 [gi:84028076]
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30
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L6 [gi:84028080]
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31
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]30S ribosomal protein S1 [gi:84028227]
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32
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]30S ribosomal protein S14 [gi:84028290]
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33
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]30S ribosomal protein S17 [gi:84028294]
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34
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L13 [gi:76363497]
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35
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L14 [gi:83287889]
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36
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L16 [gi:83287893]
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37
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L23 [gi:83287901]
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38
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]30S ribosomal protein S15 [gi:83287973]
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39
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L17 [gi:84027990]
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40
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L21 [gi:84027993]
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41
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L36 2 [gi:110816409]
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42
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L24 [gi:45593503]
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43
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L4 [gi:46397662]
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44
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L22 [gi:47117751]
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45
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]30S ribosomal protein S21 [gi:56405133]
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46
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]50S ribosomal protein L25 [gi:60393658]
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47
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]30S ribosomal protein S2 [gi:62288920]
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48
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]30S ribosomal protein S12 [gi:62288954]
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49
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]30S ribosomal protein S19 [gi:62288960]
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50
[SID124973645]
Bacterial 70S ribosome inhibitor [AID742681, Type: other]30S ribosomal protein S20 [gi:62288964]
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