Bookmark and Share
SMR000039038 (CID 54679933) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(25)
 
 
Inactive(779)
 
 
Inconclusive(36)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(27)
 
 
 
7TM GPCR Srsx(21)
 
 
alkPPc(16)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
BioAssay Types:
Screening(550)
 
 
 
 
Confirmatory(262)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(176)
 
 
 
 
 
IC50(52)
 
 
 
EC50(12)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 772    Data Row: 841   Total Pages: 17   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID856728]
IC50 5.92Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay [AID624317, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
View
2
[SID856728]
Potency 9.285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
3
[SID856728]
Potency 12.5893qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
View
4
[SID856728]
IC50_Mean 41.1Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 [AID651709, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
View
5
[SID856728]
Counterscreen for agonists of OPRM1-OPRD1 heterodimerization: luminescence-based cell-based full-deck high throughput screening assay to identify agonists of 5-hydroxytryptamine (serotonin) 5A receptor (HTR5A) [AID504692, Type: screening]5-hydroxytryptamine receptor 5A [Homo sapiens] [gi:13236497]
View
6
[SID856728]
TRFRET-based biochemical primary high throughput screening assay to identify small molecules that bind to the HIV-1-gp120 binding antibody, PG9 [AID624416, Type: screening]Envelope surface glycoprotein gp160, precursor [Human immunodeficiency virus 1] [gi:9629363]
View
7
[SID856728]
TRFRET-based biochemical high throughput confirmation assay for small molecules that bind to the HIV-1-gp120 binding antibody, PG9 [AID651571, Type: screening]Envelope surface glycoprotein gp160, precursor [Human immunodeficiency virus 1] [gi:9629363]
View
8
[SID856728]
Counterscreen for discovery of small molecules that bind to the HIV-1-gp120 binding antibody, PG9: TR-FRET-based biochemical high throughput assay to identify small molecules that bind to the control antibody, PGV04, which binds to a site on the HIV envelope different from the PG9 binding site [AID651604, Type: screening]Envelope surface glycoprotein gp160, precursor [Human immunodeficiency virus 1] [gi:9629363]
View
9
[SID856728]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
View
10
[SID856728]
Activator for delta FosB/delta FosB homodimer Measured in Biochemical System Using Plate Reader - 2072-01_Activator_SinglePoint_HTS_Activity [AID493131, Type: screening]protein fosB [Mus musculus] [gi:6679827]
View
11
[SID856728]
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624038, Type: screening]muscarinic acetylcholine receptor M5 [Homo sapiens] [gi:7108336]
View
12
[SID856728]
uHTS identification of inhibitors of NadD in a Colorimetric assay [AID602399, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
View
13
[SID856728]
Single concentration confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay [AID624309, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
View
14
[SID856728]
Inhibitors of Cav3 T-type Calcium Channels: Primary Screen [AID449739, Type: screening]voltage-dependent T-type calcium channel subunit alpha-1H isoform a [Homo sapiens] [gi:53832009]
View
15
[SID856728]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
16
[SID856728]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
17
[SID856728]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
View
18
[SID856728]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
View
19
[SID856728]
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators [AID639, Type: screening]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
View
20
[SID856728]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]BRCA1-associated RING domain protein 1 [gi:116241265]
View
21
[SID856728]
Human H69AR Lung Tumor Cell Growth Inhibition Assay - 86K Screen [AID598, Type: screening]
View
22
[SID856728]
uHTS identification of small molecule inhibitors of tim23-1 yeast via a luminescent assay [AID463212, Type: screening]TPA: Tim23p [Saccharomyces cerevisiae S288c] [gi:285814664]
View
23
[SID856728]
Primary Antimicrobial Assay for E. coli BW25113 ∆tolC::kan Protocol for 384-well HTS [AID573, Type: screening]
View
24
[SID856728]
Chemical Genetic Screen to Identify Inhibitors of Mitochondrial Fusion - Primary Screen [AID1362, Type: screening]
View
25
[SID856728]
Screening for Modulators of Post-Golgi Transport, Control Strain [AID738, Type: screening]
View
26
[SID856728]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
27
[SID856728]
Potency 3.1623qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
View
28
[SID856728]
Potency 15.8489qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen [AID720542, Type: confirmatory]apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] [gi:23496270]
View
29
[SID856728]
Potency 28.1838qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy [AID624291, Type: confirmatory]Glycoprotein hormones alpha chain [gi:121312]
View
30
[SID856728]
RNA polymerase [AID559, Type: screening]RNA polymerase beta subunit (EC 2.7.7.6), partial [Escherichia coli] [gi:147728]
View
31
[SID856728]
Counter Screen for Glucose-6-Phosphate Dehydrogenase-based Primary Assay [AID1020, Type: screening]glucose-6-phosphate dehydrogenase [Leuconostoc mesenteroides] [gi:149631]
View
32
[SID856728]
Potency qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
33
[SID856728]
Potency qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
34
[SID856728]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID758, Type: screening]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
View
35
[SID856728]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ CIT2_MLPCN. [AID2029, Type: screening]citrate synthase 2, partial [Saccharomyces cerevisiae] [gi:171229]
View
36
[SID856728]
Potency Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS [AID504937, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
37
[SID856728]
Factor XIa Mixture HTS [AID680, Type: screening]coagulation factor XI [Homo sapiens] [gi:180352]
View
38
[SID856728]
Factor XIa 1536 HTS [AID798, Type: screening]coagulation factor XI [Homo sapiens] [gi:180352]
View
39
[SID856728]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
View
40
[SID856728]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
View
41
[SID856728]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493244, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
View
42
[SID856728]
uHTS identification of agonists of the CRF-binding protein and CRF-R2 receptor complex [AID588473, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
View
43
[SID856728]
uHTS identification of antagonists of the CRF-binding protein and CRF-R2 receptor complex [AID588475, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
View
44
[SID856728]
Primary Cell Based High Throughput Screening Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) [AID571, Type: screening]5-hydroxytryptamine receptor 1E [gi:112822]
View
45
[SID856728]
Primary Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) [AID574, Type: screening]5-hydroxytryptamine receptor 1E [gi:112822]
View
46
[SID856728]
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen [AID628, Type: screening]Muscarinic acetylcholine receptor M1 [gi:113121]
View
47
[SID856728]
Potency qHTS Assay for Inhibitors of Human alpha-Galactosidase at pH 4.5. [AID1467, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
View
48
[SID856728]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate [AID2107, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
View
49
[SID856728]
Fluorescence Cell-Based Primary HTS of C.albicans growth in the presence of Fluconazole and compound [AID1979, Type: screening]heat shock protein 90 [Candida albicans] [gi:994798]
View
50
[SID856728]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. [AID1439, Type: screening]RGS7, partial [Homo sapiens] [gi:1166512]
View